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Iqck Gene Detail
Summary
  • Symbol
    Iqck
  • Name
    IQ motif containing K
  • Synonyms
    A230094G09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3612188
    NCBI Gene: 434232
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:118454975-118571343 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 63.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3474 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3612188
 protein coding gene Chr7:118454975-118571875 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032906
 protein coding gene Chr7:122737164-122860274 (+)
A/J MGP_AJ_G0032889
 protein coding gene Chr7:119600346-119719505 (+)
AKR/J MGP_AKRJ_G0032821
 protein coding gene Chr7:122658581-122782845 (+)
BALB/cJ MGP_BALBcJ_G0032894
 protein coding gene Chr7:119316291-119445914 (+)
C3H/HeJ MGP_C3HHeJ_G0032604
 protein coding gene Chr7:122556797-122681503 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033400
 protein coding gene Chr7:127614348-127751188 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030372
 protein coding gene Chr7:121035073-121152138 (+)
CAST/EiJ MGP_CASTEiJ_G0031932
 protein coding gene Chr7:114323177-114457551 (+)
CBA/J MGP_CBAJ_G0032577
 protein coding gene Chr7:131894095-132021680 (+)
DBA/2J MGP_DBA2J_G0032729
 protein coding gene Chr7:117637506-117754383 (+)
FVB/NJ MGP_FVBNJ_G0032682
 protein coding gene Chr7:117479222-117597823 (+)
LP/J MGP_LPJ_G0032823
 protein coding gene Chr7:124191959-124323224 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032714
 protein coding gene Chr7:133363864-133495067 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033420
 protein coding gene Chr7:121662459-121786035 (+)
PWK/PhJ MGP_PWKPhJ_G0031640
 protein coding gene Chr7:110542527-110663555 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031487
 protein coding gene Chr7:108382866-108509012 (+)
WSB/EiJ MGP_WSBEiJ_G0032045
 protein coding gene Chr7:122547803-122669193 (+)



Homology
more
  • Human Ortholog
    IQCK, IQ motif containing K
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IQCK, IQ motif containing K
  • Links
    NCBI Gene ID: 124152
    neXtProt AC: NX_Q8N0W5
    UniProt: Q8N0W5

  • Chr Location
    16p12.3; chr16:19716456-19858467 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 434232 NCBI Gene Model | MGI Sequence Detail 116369 C57BL/6J ±  kb
transcript NM_001374605 RefSeq | MGI Sequence Detail 1526 C57BL/6  
polypeptide NP_001361534 RefSeq | MGI Sequence Detail 290 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR043408 IQ domain-containing protein K
    IPR000048 IQ motif, EF-hand binding site
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory