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Spdye4b Gene Detail
Summary
  • Symbol
    Spdye4b
  • Name
    speedy/RINGO cell cycle regulator family, member E4B
  • Synonyms
    4933411G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3612701
    NCBI Gene: 330228
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:143166772-143190830 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 81.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    879 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3612701
 protein coding gene Chr5:143166772-143190832 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030323
 protein coding gene Chr5:148500422-148524964 (+)
A/J MGP_AJ_G0030292
 protein coding gene Chr5:142118277-142147269 (+)
AKR/J MGP_AKRJ_G0030224
 protein coding gene Chr5:146574662-146597797 (+)
BALB/cJ MGP_BALBcJ_G0030309
 protein coding gene Chr5:143363158-143397015 (+)
C3H/HeJ MGP_C3HHeJ_G0030020
 protein coding gene Chr5:147374534-147407485 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030754
 protein coding gene Chr5:153912085-153944416 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027972
 protein coding gene Chr5:135910699-135930725 (+)
CAST/EiJ MGP_CASTEiJ_G0029425
 protein coding gene Chr5:146868121-146899790 (+)
CBA/J MGP_CBAJ_G0029990
 protein coding gene Chr5:160241037-160278921 (+)
DBA/2J MGP_DBA2J_G0030140
 protein coding gene Chr5:141889569-141915842 (+)
FVB/NJ MGP_FVBNJ_G0030095
 protein coding gene Chr5:141085124-141115456 (+)
LP/J MGP_LPJ_G0030226
 protein coding gene Chr5:149090713-149118528 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030126
 protein coding gene Chr5:162670658-162694697 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030794
 protein coding gene Chr5:146412810-146441440 (+)
PWK/PhJ MGP_PWKPhJ_G0029140
 protein coding gene Chr5:140968676-140998597 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028976
 protein coding gene Chr5:144151768-144182237 (+)
WSB/EiJ MGP_WSBEiJ_G0029499
 protein coding gene Chr5:147209753-147232778 (+)



Homology
more
  • Human Ortholog
    SPDYE1, speedy/RINGO cell cycle regulator family member E1
  • Vertebrate Orthologs
    11
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPDYE1, speedy/RINGO cell cycle regulator family member E1
  • Synonyms
    Ringo1, SPDYB2L2, SPDYE, WBSCR19
  • Links
    NCBI Gene ID: 285955
    neXtProt AC: NX_Q8NFV5
    UniProt: Q8NFV5

  • Chr Location
    7p13; chr7:43997897-44010124 (+)  GRCh38
  • Human Ortholog
    SPDYE11, speedy/RINGO cell cycle regulator family member E11
  • Links
    NCBI Gene ID: 100996746
    neXtProt AC: NX_P0DTA3
    UniProt: P0DTA3

  • Chr Location
    chr7:73047862-73057911 (-)  GRCh38
  • Human Ortholog
    SPDYE13, speedy/RINGO cell cycle regulator family member E13
  • Synonyms
    SPDYE13P
  • Links
    NCBI Gene ID: 105180390

  • Chr Location
    chr7:75280790-75291806 (+)  GRCh38
  • Human Ortholog
    SPDYE14, speedy/RINGO cell cycle regulator family member E14
  • Synonyms
    SPDYE13, SPDYE14P
  • Links
    NCBI Gene ID: 641776
    UniProt: P0DUD3

  • Chr Location
    7q11.23; chr7:75237205-75317429 (+)  GRCh38
  • Human Ortholog
    SPDYE18, speedy/RINGO cell cycle regulator family member E18
  • Links
    NCBI Gene ID: 100505767
    UniProt: P0DV79

  • Chr Location
    chr7:77050391-77062558 (-)  GRCh38
  • Human Ortholog
    SPDYE21, speedy/RINGO cell cycle regulator family member E21
  • Synonyms
    SPDYE21P
  • Links
    NCBI Gene ID: 442572
    UniProt: A0A494C086

  • Chr Location
    chr7:67276941-67289005 (+)  GRCh38
  • Human Ortholog
    SPDYE4, speedy/RINGO cell cycle regulator family member E4
  • Links
    NCBI Gene ID: 388333
    neXtProt AC: NX_A6NLX3
    UniProt: A6NLX3

  • Chr Location
    17p13.1; chr17:8747524-8758559 (-)  GRCh38
  • Human Ortholog
    SPDYE5, speedy/RINGO cell cycle regulator family member E5
  • Links
    NCBI Gene ID: 442590
    neXtProt AC: NX_A6NIY4
    UniProt: A6NIY4

  • Chr Location
    chr7:75491630-75504316 (+)  GRCh38
  • Human Ortholog
    SPDYE7P, speedy/RINGO cell cycle regulator family member E7, pseudogene
  • Links
    NCBI Gene ID: 441251
    UniProt: Q495Y7

  • Chr Location
    7q11.23; chr7:72861524-72873294 (-)  GRCh38
  • Human Ortholog
    SPDYE8, speedy/RINGO cell cycle regulator family member E8
  • Synonyms
    SPDYE8P, SPDYE9
  • Links
    NCBI Gene ID: 728524
    UniProt: P0DUD1

  • Chr Location
    7q11.23; chr7:73019719-73029766 (-)  GRCh38
  • Human Ortholog
    SPDYE9, speedy/RINGO cell cycle regulator family member E9
  • Synonyms
    SPDYE9P
  • Links
    NCBI Gene ID: 643909

  • Chr Location
    7q11.23
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029586 Ensembl Gene Model | MGI Sequence Detail 24059 C57BL/6J ±  kb
    transcript ENSMUST00000031574 Ensembl | MGI Sequence Detail 2165 Not Applicable  
    polypeptide ENSMUSP00000031574 Ensembl | MGI Sequence Detail 236 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR020984 Cell cycle regulatory protein Speedy
    Molecular
    Reagents
    less
    • All nucleic 5
      Genomic 2
      cDNA 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 12
    • Earliest
      J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory