Hhla1 MGI Mouse Gene Detail - MGI:3615329

Symbol

Hhla1
Name

HERV-H LTR-associating 1
Synonyms

F930104E18Rik

Feature Type

protein coding gene
IDs

MGI:3615329
NCBI Gene: 654498
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr15:65794292-65848653 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 29.16 cM
Mapping Data

1 experiment

SNPs within 2kb

1776 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3615329	protein coding gene	Chr15:65788458-65848653 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021902	protein coding gene	Chr15:65430380-65477696 (-)
A/J	MGP_AJ_G0021861	protein coding gene	Chr15:62928221-62984270 (-)
AKR/J	MGP_AKRJ_G0021843	protein coding gene	Chr15:64687965-64741226 (-)
BALB/cJ	MGP_BALBcJ_G0021868	protein coding gene	Chr15:63114964-63168172 (-)
C3H/HeJ	MGP_C3HHeJ_G0021641	protein coding gene	Chr15:64802580-64855368 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0022307	protein coding gene	Chr15:67968225-68017602 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019844	protein coding gene	Chr15:59744367-59785577 (-)
CAST/EiJ	MGP_CASTEiJ_G0021160	protein coding gene	Chr15:65446639-65486236 (-)
CBA/J	MGP_CBAJ_G0021607	protein coding gene	Chr15:70241814-70293962 (-)
DBA/2J	MGP_DBA2J_G0021732	protein coding gene	Chr15:62725397-62776445 (-)
FVB/NJ	MGP_FVBNJ_G0021714	protein coding gene	Chr15:61764996-61817872 (-)
LP/J	MGP_LPJ_G0021804	protein coding gene	Chr15:65309269-65355866 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021737	protein coding gene	Chr15:75328894-75384678 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022329	protein coding gene	Chr15:65057352-65113681 (-)
PWK/PhJ	MGP_PWKPhJ_G0020901	protein coding gene	Chr15:62811501-62855794 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020742	protein coding gene	Chr15:64909050-64955053 (-)
WSB/EiJ	MGP_WSBEiJ_G0021212	protein coding gene	Chr15:65034944-65079948 (-)

Human Ortholog

HHLA1, HHLA1 neighbor of OC90

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

HHLA1, HHLA1 neighbor of OC90
Synonyms

PLA2L
Links

HGNC:4904

NCBI Gene ID: 10086

neXtProt AC: NX_C9JL84

UniProt: C9JL84
Chr Location

8q24.22; chr8:132061480-132111159 (-) GRCh38

MGI Vertebrate Homology

Hhla1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: HHLA1
Gene Tree

Hhla1

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References

1 with disease annotations

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Phenotype Summary

29 phenotype references

All Mutations and Alleles

21
Chemically induced (other)

3
Endonuclease-mediated

3
Gene trapped

12
Radiation induced

2
Targeted

1
Genomic Mutations

5 involving Hhla1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

26 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

29
RefSeq

2
UniProt

2
CCDS

CCDS49618.1

Ensembl

ENSMUSG00000072511 (Evidence)
NCBI Gene

654498

			Length	Strain/Species	Flank
genomic	654498	NCBI Gene Model \| MGI Sequence Detail	54362	C57BL/6J	± kb
transcript	NM_001145096	RefSeq \| MGI Sequence Detail	2262	C57BL/6
polypeptide	Q3TYV2	UniProt \| EBI \| MGI Sequence Detail	514	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000032380 HERV-H LTR-associating protein 1

(term hierarchy)
InterPro Domains

IPR037643 HERV-H LTR-associating protein 1
GlyGen

Q3TYV2 9 sites

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All nucleic 1

cDNA 1

Microarray probesets 1

Summaries

All 42

Diseases 1

Gene Ontology 1

Phenotypes 29
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

TSS for Hhla1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr134556	Chr15:65848649-65848654 (-)	1 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24