Ms4a15 MGI Mouse Gene Detail - MGI:3617853 - membrane-spanning 4-domains, subfamily A, member 15

Symbol

Ms4a15
Name

membrane-spanning 4-domains, subfamily A, member 15
Synonyms

E530011F12Rik, Gm1286, LOC383468

Feature Type

protein coding gene
IDs

MGI:3617853
NCBI Gene: 545279
Member of

Ms4ac cluster
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr19:10955671-10970614 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 7.47 cM
Mapping Data

3 experiments

SNPs within 2kb

628 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3617853	protein coding gene	Chr19:10955667-10970614 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0024866	protein coding gene	Chr19:8360256-8375199 (-)
A/J	MGP_AJ_G0024834	protein coding gene	Chr19:7796071-7811023 (-)
AKR/J	MGP_AKRJ_G0024809	protein coding gene	Chr19:8097809-8112752 (-)
BALB/cJ	MGP_BALBcJ_G0024834	protein coding gene	Chr19:7838707-7853650 (-)
C3H/HeJ	MGP_C3HHeJ_G0024600	protein coding gene	Chr19:7988047-8002994 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0025282	protein coding gene	Chr19:8713932-8728875 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022709	protein coding gene	Chr19:8211982-8227926 (-)
CAST/EiJ	MGP_CASTEiJ_G0024073	protein coding gene	Chr19:7644292-7659306 (-)
CBA/J	MGP_CBAJ_G0024574	protein coding gene	Chr19:8780521-8795463 (-)
DBA/2J	MGP_DBA2J_G0024701	protein coding gene	Chr19:7799175-7814122 (-)
FVB/NJ	MGP_FVBNJ_G0024668	protein coding gene	Chr19:7846869-7862377 (-)
LP/J	MGP_LPJ_G0024788	protein coding gene	Chr19:8312401-8327344 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024695	protein coding gene	Chr19:8665685-8680628 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025330	protein coding gene	Chr19:8119932-8134875 (-)
PWK/PhJ	MGP_PWKPhJ_G0023818	protein coding gene	Chr19:7253543-7268519 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0023623	protein coding gene	Chr19:7305736-7320880 (-)
WSB/EiJ	MGP_WSBEiJ_G0024135	protein coding gene	Chr19:8013752-8028698 (-)

Human Ortholog

MS4A15, membrane spanning 4-domains A15

Vertebrate Orthologs

20

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MS4A15, membrane spanning 4-domains A15
Links

HGNC:28573

NCBI Gene ID: 219995

neXtProt AC: NX_Q8N5U1

UniProt: Q8N5U1
Chr Location

11q12.2

MGI Vertebrate Homology

Ms4a15 stringent orthology
1 human;1 mouse;1 rat;18 zebrafish
HCOP

vertebrate homology predictions: MS4A15
Gene Tree

Ms4a15

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Phenotype Summary

1 phenotype reference

All Mutations and Alleles

2
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

16 strains or lines available

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All GO Annotations

3
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

42
RefSeq

7
UniProt

4
CCDS

CCDS29594.1

Ensembl

ENSMUSG00000067571 (Evidence)
NCBI Gene

545279

			Length	Strain/Species	Flank
genomic	ENSMUSG00000067571	Ensembl Gene Model \| MGI Sequence Detail	14944	C57BL/6J	± kb
transcript	ENSMUST00000087923	Ensembl \| MGI Sequence Detail	1713	Not Applicable
polypeptide	ENSMUSP00000085234	Ensembl \| MGI Sequence Detail	245	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000010655 membrane-spanning 4-domains subfamily A member 15

(term hierarchy)
InterPro Domains

IPR007237 CD20-like family

IPR030417 Membrane-spanning 4-domains subfamily A

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All nucleic 2

cDNA 2

Microarray probesets 2

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MGI:2686132

Summaries

All 18

Gene Ontology 2

Phenotypes 1
Earliest

J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
Latest

J:342604 UniProt-GOA, Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt. 2012;

TSS for Ms4a15:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr158267	Chr19:10970540-10970550 (-)	69 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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