Mir124a-2 MGI Mouse Gene Detail - MGI:3618700

Symbol

Mir124a-2
Name

microRNA 124a-2
Synonyms

mir-124a-2, Mirn124a-2, mmu-mir-124-2, mmu-mir-124a-2

Feature Type

miRNA gene
IDs

MGI:3618700
NCBI Gene: 723950
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr3:17849826-17849934 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 4.98 cM
Mapping Data

1 experiment

SNPs within 2kb

50 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3618700	miRNA gene	Chr3:17849826-17849934 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008627	miRNA gene	Chr3:14984245-14984353 (+)
A/J	MGP_AJ_G0008617	miRNA gene	Chr3:14907082-14907190 (+)
AKR/J	MGP_AKRJ_G0008606	miRNA gene	Chr3:15003686-15003794 (+)
BALB/cJ	MGP_BALBcJ_G0008604	miRNA gene	Chr3:14673298-14673406 (+)
C3H/HeJ	MGP_C3HHeJ_G0008546	miRNA gene	Chr3:15071113-15071221 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008818	miRNA gene	Chr3:15965232-15965340 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007790	miRNA gene	Chr3:13148652-13148760 (+)
CAST/EiJ	MGP_CASTEiJ_G0008400	miRNA gene	Chr3:15031108-15031216 (+)
CBA/J	MGP_CBAJ_G0008510	miRNA gene	Chr3:16253971-16254079 (+)
DBA/2J	MGP_DBA2J_G0008544	miRNA gene	Chr3:14504630-14504738 (+)
FVB/NJ	MGP_FVBNJ_G0008565	miRNA gene	Chr3:14201808-14201916 (+)
LP/J	MGP_LPJ_G0008634	miRNA gene	Chr3:15589400-15589508 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008528	miRNA gene	Chr3:18259372-18259480 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008799	miRNA gene	Chr3:14782271-14782379 (+)
PWK/PhJ	MGP_PWKPhJ_G0008325	miRNA gene	Chr3:14267527-14267635 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0008181	miRNA gene	Chr3:14615281-14615389 (+)
WSB/EiJ	MGP_WSBEiJ_G0008484	miRNA gene	Chr3:14845248-14845356 (+)

Human Ortholog

MIR124-2, microRNA 124-2

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR124-2, microRNA 124-2
Synonyms

mir-124-2, MIRN124-2, MIRN124A2
Links

HGNC:31503

NCBI Gene ID: 406908
Chr Location

chr8:64379149-64379257 (+) GRCh38

MGI Vertebrate Homology

Mir124a-2 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR124-2
Gene Tree

Mir124a-2

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
7 phenotypes from multigenic genotypes
7 phenotype references

All Mutations and Alleles

6
Radiation induced

1
Targeted

3
Transgenic

2
Genomic Mutations

1 involving Mir124a-2
Find Mice (IMSR)

3 strains or lines available

Mice homozygous for a null allele are viable and fertile with normal brain weight, cortical thickness, and mossy fibers

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All GO Annotations

14
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

859
Tissues

82
Literature Summary

49

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000093073 (Evidence)
NCBI Gene

723950

Representative Sequences				Length	Strain/Species	Flank
	genomic	723950	NCBI Gene Model \| MGI Sequence Detail	109	C57BL/6J	± kb
	transcript	NR_029814	RefSeq \| MGI Sequence Detail	109	C57BL/6

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All nucleic 20

Primer pair 8

Other 12

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miRBase

MI0000717

Summaries

All 79

Developmental Gene Expression 49

Diseases 1

Gene Ontology 4

Phenotypes 7
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:345099 Wang X, et al., Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development. BMC Genomics. 2024 Feb 3;25(1):139

TSS for Mir124a-2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr28485	Chr3:17848072-17848090 (+)	-1,745 bp
Tssr28486	Chr3:17848153-17848156 (+)	-1,671 bp
Tssr28487	Chr3:17848179-17848206 (+)	-1,633 bp
Tssr28488	Chr3:17848460-17848503 (+)	-1,344 bp
Tssr28489	Chr3:17849907-17849910 (+)	83 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24