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Mir125b-2 Gene Detail
Summary
  • Symbol
    Mir125b-2
  • Name
    microRNA 125b-2
  • Synonyms
    mir-125b-2, Mirn125b-2, mmu-mir-125b-2
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618706
    NCBI Gene: 723952
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr16:77443161-77443231 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 44.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618706
 miRNA gene Chr16:77443161-77443231 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008291
 miRNA gene Chr16:77778266-77778336 (+)
A/J MGP_AJ_G0008279
 miRNA gene Chr16:74345344-74345414 (+)
AKR/J MGP_AKRJ_G0008262
 miRNA gene Chr16:76579642-76579712 (+)
BALB/cJ MGP_BALBcJ_G0008264
 miRNA gene Chr16:74741364-74741434 (+)
C3H/HeJ MGP_C3HHeJ_G0008206
 miRNA gene Chr16:77035908-77035978 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008459
 miRNA gene Chr16:80268894-80268964 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007519
 miRNA gene Chr16:72810210-72810280 (+)
CAST/EiJ MGP_CASTEiJ_G0008076
 miRNA gene Chr16:77445677-77445747 (+)
CBA/J MGP_CBAJ_G0008175
 miRNA gene Chr16:83701710-83701780 (+)
DBA/2J MGP_DBA2J_G0008208
 miRNA gene Chr16:74192772-74192842 (+)
FVB/NJ MGP_FVBNJ_G0008232
 miRNA gene Chr16:73547931-73548001 (+)
LP/J MGP_LPJ_G0008290
 miRNA gene Chr16:77516039-77516109 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008196
 miRNA gene Chr16:86907991-86908061 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008449
 miRNA gene Chr16:76915103-76915173 (+)
PWK/PhJ MGP_PWKPhJ_G0007997
 miRNA gene Chr16:74390026-74390096 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007886
 miRNA gene Chr16:76536555-76536625 (+)
WSB/EiJ MGP_WSBEiJ_G0008154
 miRNA gene Chr16:77133919-77133989 (+)



Homology
more
  • Human Ortholog
    MIR125B2, microRNA 125b-2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR125B2, microRNA 125b-2
  • Synonyms
    mir-125b-2, MIRN125B2
  • Links
    NCBI Gene ID: 406912

  • Chr Location
    chr21:16590237-16590325 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    801
  • Tissues
    48
  • Literature Summary
    15
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723952 NCBI Gene Model | MGI Sequence Detail 71 C57BL/6J ±  kb
transcript NR_029540 RefSeq | MGI Sequence Detail 71 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 10
    Primer pair 3
    Other 7
Other Database
Links
less
miRBase MI0000152
References
more
  • Summaries
    All 62
    Developmental Gene Expression 15
    Diseases 1
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:101078 Smirnova L, et al., Regulation of miRNA expression during neural cell specification. Eur J Neurosci. 2005 Mar;21(6):1469-77
  • Latest
    J:354139 Ogasawara T, et al., The expression of MIR125B transcripts and bone phenotypes in Mir125b2-deficient mice. PLoS One. 2024;19(7):e0304074
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory