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Mir138-2 Gene Detail
Summary
  • Symbol
    Mir138-2
  • Name
    microRNA 138-2
  • Synonyms
    mir 138-2, Mirn138-2, mmu-mir-138-2
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618733
    NCBI Gene: 723956
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:95050939-95051009 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 46.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618733
 miRNA gene Chr8:95050939-95051009 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009137
 miRNA gene Chr8:95739409-95739479 (+)
A/J MGP_AJ_G0009118
 miRNA gene Chr8:92008102-92008172 (+)
AKR/J MGP_AKRJ_G0009108
 miRNA gene Chr8:94529488-94529558 (+)
BALB/cJ MGP_BALBcJ_G0009103
 miRNA gene Chr8:92102410-92102480 (+)
C3H/HeJ MGP_C3HHeJ_G0009042
 miRNA gene Chr8:95236050-95236120 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009344
 miRNA gene Chr8:99234389-99234459 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0008209
 miRNA gene Chr8:85824172-85824242 (+)
CAST/EiJ MGP_CASTEiJ_G0008877
 miRNA gene Chr8:94833030-94833100 (+)
CBA/J MGP_CBAJ_G0009011
 miRNA gene Chr8:102523735-102523805 (+)
DBA/2J MGP_DBA2J_G0009041
 miRNA gene Chr8:91477191-91477261 (+)
FVB/NJ MGP_FVBNJ_G0009058
 miRNA gene Chr8:90444339-90444409 (+)
LP/J MGP_LPJ_G0009137
 miRNA gene Chr8:95889611-95889681 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0009024
 miRNA gene Chr8:104821284-104821354 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009314
 miRNA gene Chr8:94690261-94690331 (+)
PWK/PhJ MGP_PWKPhJ_G0008804
 miRNA gene Chr8:90854423-90854493 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008645
 miRNA gene Chr8:93516614-93516684 (+)
WSB/EiJ MGP_WSBEiJ_G0008971
 miRNA gene Chr8:95210621-95210691 (+)



Homology
more
  • Human Ortholog
    MIR138-2, microRNA 138-2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR138-2, microRNA 138-2
  • Synonyms
    mir-138-2, MIRN138-2
  • Links
    NCBI Gene ID: 406930

  • Chr Location
    chr16:56858518-56858601 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    13
  • Literature Summary
    10
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723956 NCBI Gene Model | MGI Sequence Detail 71 C57BL/6J ±  kb
transcript NR_029552 RefSeq | MGI Sequence Detail 71 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Primer pair 1
    Other 2
Other Database
Links
less
miRBase MI0000164
References
more
  • Summaries
    All 24
    Developmental Gene Expression 10
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:318524 Bai XZ, et al., MicroRNA-138 Aggravates Inflammatory Responses of Macrophages by Targeting SIRT1 and Regulating the NF-kappaB and AKT Pathways. Cell Physiol Biochem. 2018;49(2):489-500
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory