Mir96 MGI Mouse Gene Detail - MGI:3619440

Symbol

Mir96
Name

microRNA 96
Synonyms

mir 96, Mirn96, mmu-mir-96

Feature Type

miRNA gene
IDs

MGI:3619440
NCBI Gene: 723886
Member of

Mirc35 cluster, Mirc40 cluster
Alliance

gene page

Sequence Map

Chr6:30169445-30169550 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 12.52 cM
Mapping Data

1 experiment

SNPs within 2kb

72 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619440	miRNA gene	Chr6:30169445-30169550 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0008889	miRNA gene	Chr6:28022627-28022732 (-)
A/J	MGP_AJ_G0008874	miRNA gene	Chr6:26824443-26824548 (-)
AKR/J	MGP_AKRJ_G0008864	miRNA gene	Chr6:27709468-27709573 (-)
BALB/cJ	MGP_BALBcJ_G0008862	miRNA gene	Chr6:26981975-26982080 (-)
C3H/HeJ	MGP_C3HHeJ_G0008801	miRNA gene	Chr6:27711651-27711756 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0009091	miRNA gene	Chr6:28832796-28832901 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0008012	miRNA gene	Chr6:25032811-25032916 (-)
CAST/EiJ	MGP_CASTEiJ_G0008644	miRNA gene	Chr6:27523448-27523553 (-)
CBA/J	MGP_CBAJ_G0008768	miRNA gene	Chr6:29907993-29908098 (-)
DBA/2J	MGP_DBA2J_G0008800	miRNA gene	Chr6:26762581-26762686 (-)
FVB/NJ	MGP_FVBNJ_G0008818	miRNA gene	Chr6:26523290-26523395 (-)
LP/J	MGP_LPJ_G0008893	miRNA gene	Chr6:28158008-28158113 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008784	miRNA gene	Chr6:32383635-32383740 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0009068	miRNA gene	Chr6:27597854-27597959 (-)
PWK/PhJ	MGP_PWKPhJ_G0008571	miRNA gene	Chr6:26323702-26323807 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0008416	miRNA gene	Chr6:27331720-27331825 (-)
WSB/EiJ	MGP_WSBEiJ_G0008740	miRNA gene	Chr6:27568324-27568429 (-)

Human Ortholog

MIR96, microRNA 96

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR96, microRNA 96
Synonyms

DFNA50, hsa-mir-96, miR-96, MIRN96, miRNA96
Links

HGNC:31648

NCBI Gene ID: 407053
Chr Location

chr7:129774692-129774769 (-) GRCh38

MGI Vertebrate Homology

Mir96 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR96
Gene Tree

Mir96

Diseases

2 with human MIR96 associations

				Human Disease	Mouse Models
				attention deficit hyperactivity disorder IDs attention deficit hyperactivity disorder DOID:1094 DOID:1093 EFO:0003888 ICD9CM:314.8 MESH:D001289 OMIM:143465 OMIM:608903 OMIM:608904 OMIM:608905 OMIM:608906 OMIM:612311 OMIM:612312 UMLS_CUI:C0041671
				autosomal dominant nonsyndromic deafness 50 IDs autosomal dominant nonsyndromic deafness 50 DOID:0110576 ICD10CM:H90.3 OMIM:613074

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

15 phenotypes from 2 alleles in 2 genetic backgrounds
16 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Chemically induced (ENU)

1
Endonuclease-mediated

3
Targeted

6
Genomic Mutations

1 involving Mir96
Find Mice (IMSR)

8 strains or lines available

Mice homozygous and heterozygous for an ENU-induced mutation exhibit hearing loss associated with hair cell degeneration.

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All GO Annotations

16
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

843
Tissues

69
Literature Summary

19

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000065586 (Evidence)
NCBI Gene

723886

Representative Sequences				Length	Strain/Species	Flank
	genomic	723886	NCBI Gene Model \| MGI Sequence Detail	106	C57BL/6J	± kb
	transcript	NR_029750	RefSeq \| MGI Sequence Detail	106	C57BL/6

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All nucleic 17

Primer pair 9

Other 8

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miRBase

MI0000583

Summaries

All 63

Developmental Gene Expression 19

Gene Ontology 6

Phenotypes 16
Earliest

J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
Latest

J:357737 Rao F, et al., Overexpression of miR-96 leads to retinal degeneration in mice. Biochem Biophys Res Commun. 2024 Jul 30;719:150048

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24