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Mir499 Gene Detail
Summary
  • Symbol
    Mir499
  • Name
    microRNA 499
  • Synonyms
    mir 499, Mirn499, mmu-mir-499
  • Feature Type
    miRNA gene
  • IDs
    MGI:3629633
    NCBI Gene: 735275
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:155464800-155464878 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 77.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    96 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629633
 miRNA gene Chr2:155464800-155464878 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008601
 miRNA gene Chr2:160458780-160458858 (+)
A/J MGP_AJ_G0008589
 miRNA gene Chr2:154079026-154079104 (+)
AKR/J MGP_AKRJ_G0008576
 miRNA gene Chr2:158547629-158547707 (+)
BALB/cJ MGP_BALBcJ_G0008577
 miRNA gene Chr2:154381952-154382030 (+)
C3H/HeJ MGP_C3HHeJ_G0008518
 miRNA gene Chr2:158910421-158910499 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008787
 miRNA gene Chr2:165159752-165159830 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007766
 miRNA gene Chr2:147578568-147578646 (+)
CAST/EiJ MGP_CASTEiJ_G0008375
 miRNA gene Chr2:159223170-159223248 (+)
CBA/J MGP_CBAJ_G0008484
 miRNA gene Chr2:171160551-171160629 (+)
DBA/2J MGP_DBA2J_G0008517
 miRNA gene Chr2:153259887-153259965 (+)
FVB/NJ MGP_FVBNJ_G0008538
 miRNA gene Chr2:151637531-151637609 (+)
LP/J MGP_LPJ_G0008608
 miRNA gene Chr2:160601490-160601568 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008500
 miRNA gene Chr2:175152971-175153049 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008772
 miRNA gene Chr2:158434983-158435061 (+)
PWK/PhJ MGP_PWKPhJ_G0008297
 miRNA gene Chr2:152757271-152757349 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008155
 miRNA gene Chr2:157361394-157361472 (+)
WSB/EiJ MGP_WSBEiJ_G0008459
 miRNA gene Chr2:159322556-159322634 (+)



Homology
more
  • Human Ortholog
    MIR499A, microRNA 499a
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR499A, microRNA 499a
  • Synonyms
    hsa-mir-499a, MIR499, mir-499a, MIRN499
  • Links
    NCBI Gene ID: 574501

  • Chr Location
    chr20:34990376-34990497 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit no overt abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    21
  • Literature Summary
    4
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 735275 NCBI Gene Model | MGI Sequence Detail 79 C57BL/6J ±  kb
transcript NR_030757 RefSeq | MGI Sequence Detail 79 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    Primer pair 2
    Other 3
Other Database
Links
less
miRBase MI0004676
References
more
  • Summaries
    All 22
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:326951 Wildung M, et al., miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly. Int J Mol Sci. 2022 Jul 13;23(14)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory