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Mir491 Gene Detail
Summary
  • Symbol
    Mir491
  • Name
    microRNA 491
  • Synonyms
    mir 491, Mirn491, mmu-mir-491
  • Feature Type
    miRNA gene
  • IDs
    MGI:3629651
    NCBI Gene: 735282
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:88040277-88040362 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 41.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629651
 miRNA gene Chr4:88040277-88040362 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008735
 miRNA gene Chr4:87966711-87966796 (+)
A/J MGP_AJ_G0008719
 miRNA gene Chr4:84923063-84923148 (+)
AKR/J MGP_AKRJ_G0008711
 miRNA gene Chr4:87013603-87013688 (+)
BALB/cJ MGP_BALBcJ_G0008709
 miRNA gene Chr4:85124669-85124754 (+)
C3H/HeJ MGP_C3HHeJ_G0008650
 miRNA gene Chr4:87739325-87739410 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008928
 miRNA gene Chr4:91352932-91353017 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007876
 miRNA gene Chr4:80927444-80927529 (+)
CAST/EiJ MGP_CASTEiJ_G0008491
 miRNA gene Chr4:85593594-85593679 (+)
CBA/J MGP_CBAJ_G0008615
 miRNA gene Chr4:94166563-94166648 (+)
DBA/2J MGP_DBA2J_G0008645
 miRNA gene Chr4:84685863-84685948 (+)
FVB/NJ MGP_FVBNJ_G0008667
 miRNA gene Chr4:83625639-83625724 (+)
LP/J MGP_LPJ_G0008740
 miRNA gene Chr4:88328670-88328755 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008632
 miRNA gene Chr4:99155195-99155280 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008909
 miRNA gene Chr4:87140400-87140485 (+)
PWK/PhJ MGP_PWKPhJ_G0008420
 miRNA gene Chr4:83015412-83015497 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008272
 miRNA gene Chr4:84648189-84648274 (+)
WSB/EiJ MGP_WSBEiJ_G0008588
 miRNA gene Chr4:87364431-87364516 (+)



Homology
more
  • Human Ortholog
    MIR491, microRNA 491
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR491, microRNA 491
  • Synonyms
    hsa-mir-491, mir-491, MIRN491
  • Links
    NCBI Gene ID: 574444

  • Chr Location
    chr9:20716105-20716188 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    5 involving Mir491
  • Find Mice (IMSR)
    1 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 735282 NCBI Gene Model | MGI Sequence Detail 86 C57BL/6J ±  kb
transcript NR_030478 RefSeq | MGI Sequence Detail 86 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
miRBase MI0004680
References
more
  • Summaries
    All 15
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:249295 He J, et al., miR-491 inhibits skeletal muscle differentiation through targeting myomaker. Arch Biochem Biophys. 2017 Jul 1;625-626:30-38
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory