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Igkv8-28 Gene Detail
Summary
  • Symbol
    Igkv8-28
  • Name
    immunoglobulin kappa variable 8-28
  • Synonyms
    ENSMUSG00000073023
  • Feature Type
    gene segment
  • IDs
    MGI:3642251
    NCBI Gene: 434040
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr6:70120577-70121145 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 31.78 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642251
 gene segment Chr6:70120577-70121150 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0000151
 gene segment Chr6:67707838-67708357 (-)
AKR/J MGP_AKRJ_G0000151
 gene segment Chr6:69779058-69779362 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0000106
 gene segment Chr6:114458249-114458553 (+)
C57BL/6NJ MGP_C57BL6NJ_G0000206
 gene segment Chr6:72263008-72263581 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0000082
 gene segment Chr6:67232116-67232694 (-)
CAST/EiJ MGP_CASTEiJ_G0000156
 gene segment Chr6:69699580-69699876 (+)
CBA/J MGP_CBAJ_G0000148
 gene segment Chr6:75187180-75187484 (-)
DBA/2J MGP_DBA2J_G0000142
 gene segment Chr6:67205146-67205450 (-)
FVB/NJ MGP_FVBNJ_G0000140
 gene segment Chr6:66558508-66559040 (-)
LP/J MGP_LPJ_G0000173
 gene segment Chr6:70349298-70352180 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0000188
 gene segment Chr6:69594900-69595473 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0000108
 gene segment Chr6:68455669-68456246 (-)
WSB/EiJ MGP_WSBEiJ_G0000148
 gene segment Chr6:69894464-69895041 (-)



Homology
more
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Synonyms
    B3, IGKV41
  • Links
    NCBI Gene ID: 28908
    UniProt: P06312

  • Chr Location
    2p11.2; chr2:88885397-88886153 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 434040 NCBI Gene Model | MGI Sequence Detail 569 C57BL/6J ±  kb
polypeptide A0A0G2JE47 UniProt | EBI | MGI Sequence Detail 121 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR050150 Immunoglobulin Variable Light Chain
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 9
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory