Trav6-2 Gene Detail

Summary

• Symbol
  Trav6-2
• Name
  T cell receptor alpha variable 6-2
• Synonyms
  TRAV6-2

• Feature Type
  gene segment
• IDs
  MGI:3642602
  NCBI Gene: 436539
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:52904868-52905321 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.04 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  56 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3642602	gene segment	Chr14:52904868-52905321 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0002523	gene segment	Chr14:46722060-46722513 (+)
A/J	MGP_AJ_G0002494	gene segment	Chr14:45502160-45502613 (+)
AKR/J	MGP_AKRJ_G0002481	gene segment	Chr14:47151542-47151995 (+)
BALB/cJ	MGP_BALBcJ_G0002490	gene segment	Chr14:45605527-45605980 (+)
C3H/HeJ	MGP_C3HHeJ_G0002466	gene segment	Chr14:46910063-46910516 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0002616	gene segment	Chr14:48796523-48796976 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0002224	gene segment	Chr14:44607015-44607468 (+)
CAST/EiJ	MGP_CASTEiJ_G0002427	gene segment	Chr14:43871200-43871652 (+)
CBA/J	MGP_CBAJ_G0002457	gene segment	Chr14:50281522-50281975 (+)
DBA/2J	MGP_DBA2J_G0002463	gene segment	Chr14:45263129-45263582 (+)
FVB/NJ	MGP_FVBNJ_G0002480	gene segment	Chr14:44839757-44840210 (+)
LP/J	MGP_LPJ_G0002519	gene segment	Chr14:47352349-47352802 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0002448	gene segment	Chr14:49727360-49727813 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0002612	gene segment	Chr14:46493030-46493483 (+)
PWK/PhJ	MGP_PWKPhJ_G0002409	gene segment	Chr14:42017312-42017765 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0002341	gene segment	Chr14:42531603-42532056 (+)
WSB/EiJ	MGP_WSBEiJ_G0002457	gene segment	Chr14:46813123-46813576 (+)

Homology

• Human Ortholog
  TRAV9-2, T cell receptor alpha variable 9-2

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TRAV9-2, T cell receptor alpha variable 9-2
  
• Synonyms
  TCRAV22S1, TCRAV9S2, TRAV92
• Links
  HGNC:12154

  NCBI Gene ID: 28677

  UniProt: A0A087WT02

  
  
• Chr Location
  14q11.2; chr14:21941128-21941657 (+)  GRCh38

---

• MGI Vertebrate Homology
  Trav6-2 stringent orthology
  1 human;1 mouse;2 zebrafish
  
• HCOP
  vertebrate homology predictions: TRAV9-2
• Gene Tree
  Trav6-2
  

Mutations,
Alleles, and
Phenotypes

• Incidental Mutations
  APF
• Find Mice (IMSR)
  9 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  26
• RefSeq
  2
• UniProt
  1

• Ensembl
  ENSMUSG00000076764 (Evidence)
• NCBI Gene
  436539

Representative Sequences			Length	Strain/Species
genomic	436539	NCBI Gene Model | MGI Sequence Detail	454	C57BL/6J
polypeptide	Q5R1I4	UniProt | EBI | MGI Sequence Detail	113	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain
  IPR051287 T cell receptor variable region

Molecular
Reagents

• 
  

  Microarray probesets 2

References

• Summaries
  All 11
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Trav6-2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125471	Chr14:52904813-52904840 (+)	-41 bp