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Triml2 Gene Detail
Summary
  • Symbol
    Triml2
  • Name
    tripartite motif family-like 2
  • Synonyms
    EG622117
  • Feature Type
    protein coding gene
  • IDs
    MGI:3642989
    NCBI Gene: 622117
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:43633578-43646918 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 23.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    546 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642989
 protein coding gene Chr8:43633500-43646921 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033565
 protein coding gene Chr8:42098003-42108703 (+)
A/J MGP_AJ_G0033548
 protein coding gene Chr8:40503048-40514788 (+)
AKR/J MGP_AKRJ_G0033471
 protein coding gene Chr8:41667694-41678394 (+)
BALB/cJ MGP_BALBcJ_G0033543
 protein coding gene Chr8:40631144-40641844 (+)
C3H/HeJ MGP_C3HHeJ_G0033253
 protein coding gene Chr8:42099052-42109805 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034059
 protein coding gene Chr8:43670088-43682548 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031009
 protein coding gene Chr8:36967028-36978050 (+)
CAST/EiJ MGP_CASTEiJ_G0032581
 protein coding gene Chr8:41584845-41595522 (+)
CBA/J MGP_CBAJ_G0033231
 protein coding gene Chr8:45485526-45496226 (+)
DBA/2J MGP_DBA2J_G0033385
 protein coding gene Chr8:40311647-40322398 (+)
FVB/NJ MGP_FVBNJ_G0033329
 protein coding gene Chr8:39851964-39862664 (+)
LP/J MGP_LPJ_G0033474
 protein coding gene Chr8:42176538-42187238 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033371
 protein coding gene Chr8:45541881-45552581 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034077
 protein coding gene Chr8:41901852-41914870 (+)
PWK/PhJ MGP_PWKPhJ_G0032290
 protein coding gene Chr8:39859077-39869866 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032122
 protein coding gene Chr8:41055900-41066628 (+)
WSB/EiJ MGP_WSBEiJ_G0032696
 protein coding gene Chr8:42079303-42090001 (+)



Homology
more
  • Human Ortholog
    TRIML2, tripartite motif family like 2
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIML2, tripartite motif family like 2
  • Synonyms
    SPRYD6
  • Links
    NCBI Gene ID: 205860
    neXtProt AC: NX_Q8N7C3
    UniProt: Q8N7C3

  • Chr Location
    4q35.2; chr4:188091272-188109603 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091490 Ensembl Gene Model | MGI Sequence Detail 13341 C57BL/6J ±  kb
transcript ENSMUST00000209200 Ensembl | MGI Sequence Detail 1519 Not Applicable  
polypeptide ENSMUSP00000147371 Ensembl | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:330283 Ringel AR, et al., Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes. Cell. 2022 Sep 29;185(20):3689-3704.e21
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory