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Insyn2b Gene Detail
Summary
  • Symbol
    Insyn2b
  • Name
    inhibitory synaptic factor family member 2B
  • Synonyms
    Fam196b, Gm6041
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643491
    NCBI Gene: 574403
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:34264822-34372642 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643491
 protein coding gene Chr11:34264758-34372642 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018152
 protein coding gene Chr11:32649117-32765329 (+)
A/J MGP_AJ_G0018125
 protein coding gene Chr11:31423096-31532838 (+)
AKR/J MGP_AKRJ_G0018089
 protein coding gene Chr11:32388897-32495523 (+)
BALB/cJ MGP_BALBcJ_G0018094
 protein coding gene Chr11:31597155-31705938 (+)
C3H/HeJ MGP_C3HHeJ_G0017907
 protein coding gene Chr11:32338510-32452714 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018548
 protein coding gene Chr11:33687297-33800262 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016203
 protein coding gene Chr11:29911752-30018192 (+)
CAST/EiJ MGP_CASTEiJ_G0017471
 protein coding gene Chr11:32451144-32566694 (+)
CBA/J MGP_CBAJ_G0017880
 protein coding gene Chr11:35357810-35482692 (+)
DBA/2J MGP_DBA2J_G0017990
 protein coding gene Chr11:31183711-31291154 (+)
FVB/NJ MGP_FVBNJ_G0017984
 protein coding gene Chr11:31015665-31125840 (+)
LP/J MGP_LPJ_G0018062
 protein coding gene Chr11:32914745-33021825 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018008
 protein coding gene Chr11:36248377-36360407 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018587
 protein coding gene Chr11:32548084-32662993 (+)
PWK/PhJ MGP_PWKPhJ_G0017252
 protein coding gene Chr11:31377187-31486707 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017044
 protein coding gene Chr11:32281977-32389716 (+)
WSB/EiJ MGP_WSBEiJ_G0017520
 protein coding gene Chr11:32184992-32295928 (+)



Homology
more
  • Human Ortholog
    INSYN2B, inhibitory synaptic factor family member 2B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INSYN2B, inhibitory synaptic factor family member 2B
  • Synonyms
    C5orf57, FAM196B
  • Links
    NCBI Gene ID: 100131897
    neXtProt AC: NX_A6NMK8
    UniProt: A6NMK8

  • Chr Location
    5q35.1; chr5:169861303-169980495 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    5
  • cDNA Data
    7
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 574403 NCBI Gene Model | MGI Sequence Detail 107821 C57BL/6J ±  kb
    transcript NM_001025382 RefSeq | MGI Sequence Detail 5415 C57BL/6  
    polypeptide Q6GQV1 UniProt | EBI | MGI Sequence Detail 535 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 7
      Primer pair 3
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:6286263
    References
    more
    • Summaries
      All 23
      Developmental Gene Expression 3
      Phenotypes 7
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory