Fam169b Gene Detail

Summary

• Symbol
  Fam169b
• Name
  family with sequence similarity 169, member B
• Synonyms
  EG434197

• Feature Type
  protein coding gene
• IDs
  MGI:3644026
  NCBI Gene: 434197
• Alliance
  gene page
• Transcription Start Sites
  26 TSS

Location &
Maps

• Sequence Map
  Chr7:67923587-68012837 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 37.49 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  2739 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3644026	protein coding gene	Chr7:67923587-68012840 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007190	lincRNA gene	Chr7:69583552-69675859 (+)
A/J	MGP_AJ_G0007186	lincRNA gene	Chr7:68127388-68220127 (+)
AKR/J	MGP_AKRJ_G0007156	lincRNA gene	Chr7:69570711-69667696 (+)
BALB/cJ	MGP_BALBcJ_G0007165	lincRNA gene	Chr7:67874343-67963532 (+)
C3H/HeJ	MGP_C3HHeJ_G0007108	lincRNA gene	Chr7:70281662-70372617 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007334	lincRNA gene	Chr7:72523955-72617519 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006543	lincRNA gene	Chr7:70976209-71060527 (+)
CAST/EiJ	MGP_CASTEiJ_G0007010	lincRNA gene	Chr7:60956380-61053636 (+)
CBA/J	MGP_CBAJ_G0007091	lincRNA gene	Chr7:74799534-74895428 (+)
DBA/2J	MGP_DBA2J_G0007112	lincRNA gene	Chr7:66832796-66924024 (+)
FVB/NJ	MGP_FVBNJ_G0007135	lincRNA gene	Chr7:66956777-67052977 (+)
LP/J	MGP_LPJ_G0007194	lincRNA gene	Chr7:70791659-70887078 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007112	lincRNA gene	Chr7:75003630-75098642 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007337	lincRNA gene	Chr7:68955213-69057125 (+)
PWK/PhJ	MGP_PWKPhJ_G0006953	lincRNA gene	Chr7:59897683-59991692 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0006861	lincRNA gene	Chr7:55986167-56084566 (+)
WSB/EiJ	MGP_WSBEiJ_G0007072	lincRNA gene	Chr7:69283597-69378521 (+)

Homology

• Human Ortholog
  FAM169BP, protein FAM169B

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FAM169BP, protein FAM169B
  
• Synonyms
  FAM169B
• Links
  HGNC:26835

  NCBI Gene ID: 283777

  neXtProt AC: NX_Q8N8A8

  UniProt: Q8N8A8

  
  
• Chr Location
  15q26.3; chr15:98437162-98520386 (-)  GRCh38

---

• MGI Vertebrate Homology
  Fam169b stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: FAM169BP
• Gene Tree
  Fam169b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  13 phenotype references
  

• All Mutations and Alleles
  35
• Chemically induced (other)
  1
• Gene trapped
  33
• Radiation induced
  1
• Genomic Mutations
  2 involving Fam169b
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  49 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  706
• cDNA Data
  9

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  44
• RefSeq
  12
• UniProt
  2
• CCDS
  CCDS85317.1, CCDS90253.1

• Ensembl
  ENSMUSG00000074071 (Evidence)
• NCBI Gene
  434197

Representative Sequences			Length	Strain/Species
genomic	434197	NCBI Gene Model | MGI Sequence Detail	89251	C57BL/6J
transcript	NM_001013811	RefSeq | MGI Sequence Detail	2818	C57BL/6
polypeptide	Q8CHT6	UniProt | EBI | MGI Sequence Detail	337	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR029625 Protein FAM169

Molecular
Reagents

• All nucleic 11

  Genomic 2

  cDNA 9

  
  

  Microarray probesets 2

References

• Summaries
  All 27

  Phenotypes 13
• Earliest
  J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Fam169b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr67125	Chr7:67924265-67924270 (+)	681 bp
Tssr67126	Chr7:67925616-67925627 (+)	2,035 bp
Tssr67127	Chr7:67925712-67925714 (+)	2,126 bp
Tssr67128	Chr7:67925718-67925773 (+)	2,159 bp
Tssr67129	Chr7:67925856-67925882 (+)	2,282 bp
Tssr67130	Chr7:67927278-67927287 (+)	3,696 bp
Tssr67131	Chr7:67927495-67927503 (+)	3,912 bp
Tssr67132	Chr7:67928914-67928929 (+)	5,335 bp
Tssr67133	Chr7:67928944-67928949 (+)	5,360 bp
Tssr67134	Chr7:67928951-67928957 (+)	5,367 bp
Tssr67135	Chr7:67928965-67928974 (+)	5,383 bp
Tssr67136	Chr7:67932654-67932679 (+)	9,080 bp
Tssr2297	Chr7:67932699-67932706 (+)	9,116 bp
Tssr67137	Chr7:67933551-67933553 (+)	9,965 bp
Tssr2298	Chr7:67933893-67933917 (+)	10,318 bp
Tssr67138	Chr7:67935881-67935901 (+)	12,304 bp
Tssr67139	Chr7:67935914-67935926 (+)	12,333 bp
Tssr67140	Chr7:67935930-67935954 (+)	12,355 bp
Tssr67141	Chr7:67936869-67936878 (+)	13,287 bp
Tssr67142	Chr7:67936928-67936951 (+)	13,353 bp
Tssr67143	Chr7:67937168-67937186 (+)	13,590 bp
Tssr67144	Chr7:67937957-67937967 (+)	14,375 bp
Tssr67145	Chr7:67939224-67939228 (+)	15,639 bp
Tssr67146	Chr7:67939294-67939298 (+)	15,709 bp
Tssr67147	Chr7:67978992-67979032 (+)	55,425 bp
Tssr67148	Chr7:67988085-67988088 (+)	64,500 bp