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Otud6a Gene Detail
Summary
  • Symbol
    Otud6a
  • Name
    OTU domain containing 6A
  • Synonyms
    EG408193
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644685
    NCBI Gene: 408193
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:99472619-99473491 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 43.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644685
 protein coding gene ChrX:99472514-99474859 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035940
 protein coding gene ChrX:96879610-96880482 (+)
A/J MGP_AJ_G0035925
 protein coding gene ChrX:96918270-96919142 (+)
AKR/J MGP_AKRJ_G0035841
 protein coding gene ChrX:99707410-99708282 (+)
BALB/cJ MGP_BALBcJ_G0035908
 protein coding gene ChrX:95676425-95677297 (+)
C3H/HeJ MGP_C3HHeJ_G0035617
 protein coding gene ChrX:97317315-97318187 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036437
 protein coding gene ChrX:99788113-99788985 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033267
 protein coding gene ChrX:94713553-94714425 (+)
CAST/EiJ MGP_CASTEiJ_G0034904
 protein coding gene ChrX:81622088-81622960 (+)
CBA/J MGP_CBAJ_G0035592
 protein coding gene ChrX:102875871-102876743 (+)
DBA/2J MGP_DBA2J_G0035746
 protein coding gene ChrX:96134981-96135853 (+)
FVB/NJ MGP_FVBNJ_G0035684
 protein coding gene ChrX:95537283-95538155 (+)
LP/J MGP_LPJ_G0035836
 protein coding gene ChrX:97855518-97856390 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035719
 protein coding gene ChrX:107397454-107398326 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036464
 protein coding gene ChrX:96586616-96587488 (+)
PWK/PhJ MGP_PWKPhJ_G0034603
 protein coding gene ChrX:79242841-79243713 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034431
 protein coding gene ChrX:82497022-82497894 (+)
WSB/EiJ MGP_WSBEiJ_G0035043
 protein coding gene ChrX:95313838-95314710 (+)



Homology
more
  • Human Ortholog
    OTUD6A, OTU deubiquitinase 6A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OTUD6A, OTU deubiquitinase 6A
  • Synonyms
    DUBA2, HSHIN6
  • Links
    NCBI Gene ID: 139562
    neXtProt AC: NX_Q7L8S5
    UniProt: Q7L8S5

  • Chr Location
    Xq13.1; chrX:70062457-70064179 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051582 Ensembl Gene Model | MGI Sequence Detail 873 C57BL/6J ±  kb
    transcript ENSMUST00000060241 Ensembl | MGI Sequence Detail 873 Not Applicable  
    polypeptide ENSMUSP00000059861 Ensembl | MGI Sequence Detail 290 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 1
    References
    more
    • Summaries
      All 25
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory