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Ces3b Gene Detail
Summary
  • Symbol
    Ces3b
  • Name
    carboxylesterase 3B
  • Synonyms
    ES31L, Gm4738
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644960
    NCBI Gene: 13909
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105810385-105820561 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    381 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644960
 protein coding gene Chr8:105810365-105820561 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034026
 protein coding gene Chr8:107273908-107284074 (+)
A/J MGP_AJ_G0034007
 protein coding gene Chr8:103058455-103068915 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0034000
 protein coding gene Chr8:103186262-103231286 (+)
C3H/HeJ MGP_C3HHeJ_G0033712
 protein coding gene Chr8:106763545-106778612 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034520
 protein coding gene Chr8:111184740-111340363 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017461
 protein coding gene Chr11:112768754-112780345 (+)
CAST/EiJ MGP_CASTEiJ_G0033038
 protein coding gene Chr8:106261455-106271232 (+)
CBA/J MGP_CBAJ_G0033685
 protein coding gene Chr8:114833420-114847304 (+)
DBA/2J MGP_DBA2J_G0033840
 protein coding gene Chr8:102344754-102359193 (+)
FVB/NJ MGP_FVBNJ_G0033786
 protein coding gene Chr8:101325037-101335026 (+)
LP/J MGP_LPJ_G0033931
 protein coding gene Chr8:107452081-107472708 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033829
 protein coding gene Chr8:118019333-118075940 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034538
 protein coding gene Chr8:105998296-106009262 (+)
PWK/PhJ MGP_PWKPhJ_G0032739
 protein coding gene Chr8:101788169-101793574 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032580
 protein coding gene Chr8:104646727-104650428 (+)
WSB/EiJ MGP_WSBEiJ_G0033154
 protein coding gene Chr8:106637231-106650691 (+)



Homology
more
  • Human Ortholog
    CES3, carboxylesterase 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CES3, carboxylesterase 3
  • Synonyms
    ES31
  • Links
    NCBI Gene ID: 23491
    neXtProt AC: NX_Q6UWW8
    UniProt: Q6UWW8

  • Chr Location
    16q22.1; chr16:66961245-66975149 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    37
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062181 Ensembl Gene Model | MGI Sequence Detail 10177 C57BL/6J ±  kb
transcript ENSMUST00000093221 Ensembl | MGI Sequence Detail 2403 Not Applicable  
polypeptide ENSMUSP00000090909 Ensembl | MGI Sequence Detail 571 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:13160 Aida K, et al., Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver. Biochim Biophys Acta. 1993 Jul 18;1174(1):72-4
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory