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Wdr49 Gene Detail
Summary
  • Symbol
    Wdr49
  • Name
    WD repeat domain 49
  • Synonyms
    EG213248
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645287
    NCBI Gene: 213248
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:75182295-75389463 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 33.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5530 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645287
 protein coding gene Chr3:75181235-75389472 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027305
 protein coding gene Chr3:74762434-74948353 (-)
A/J MGP_AJ_G0027267
 protein coding gene Chr3:72449875-72624729 (-)
AKR/J MGP_AKRJ_G0027235
 protein coding gene Chr3:74091837-74274249 (-)
BALB/cJ MGP_BALBcJ_G0027278
 protein coding gene Chr3:72422219-72615915 (-)
C3H/HeJ MGP_C3HHeJ_G0027022
 protein coding gene Chr3:74394155-74592473 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027724
 protein coding gene Chr3:77714041-77912265 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025077
 protein coding gene Chr3:68297486-68455183 (-)
CAST/EiJ MGP_CASTEiJ_G0026469
 protein coding gene Chr3:74346974-74533094 (-)
CBA/J MGP_CBAJ_G0026997
 protein coding gene Chr3:80175220-80396369 (-)
DBA/2J MGP_DBA2J_G0027133
 protein coding gene Chr3:71993800-72180396 (-)
FVB/NJ MGP_FVBNJ_G0027101
 protein coding gene Chr3:70399692-70568008 (-)
LP/J MGP_LPJ_G0027241
 protein coding gene Chr3:75785533-75956194 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027120
 protein coding gene Chr3:86002764-86207924 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027782
 protein coding gene Chr3:73909686-74092669 (-)
PWK/PhJ MGP_PWKPhJ_G0026203
 protein coding gene Chr3:71728493-71898150 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026019
 protein coding gene Chr3:72989426-73170995 (-)
WSB/EiJ MGP_WSBEiJ_G0026547
 protein coding gene Chr3:74166567-74364622 (-)



Homology
more
  • Human Ortholog
    WDR49, WD repeat domain 49
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR49, WD repeat domain 49
  • Synonyms
    CFAP337
  • Links
    NCBI Gene ID: 151790
    UniProt: Q8IV35

  • Chr Location
    3q26.1; chr3:167478684-167657923 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000104301 Ensembl Gene Model | MGI Sequence Detail 207169 C57BL/6J ±  kb
    transcript ENSMUST00000193989 Ensembl | MGI Sequence Detail 2413 Not Applicable  
    polypeptide ENSMUSP00000144721 Ensembl | MGI Sequence Detail 710 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 16
      Diseases 1
      Phenotypes 7
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory