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Aadacl2 Gene Detail
Summary
  • Symbol
    Aadacl2
  • Name
    arylacetamide deacetylase like 2
  • Synonyms
    EG639634
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646333
    NCBI Gene: 639634
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:59914164-59932841 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 29.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    447 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646333
 protein coding gene Chr3:59914164-59932841 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027251
 protein coding gene Chr3:58880548-58900573 (+)
A/J MGP_AJ_G0027211
 protein coding gene Chr3:57170333-57188302 (+)
AKR/J MGP_AKRJ_G0027181
 protein coding gene Chr3:58282247-58300153 (+)
BALB/cJ MGP_BALBcJ_G0027224
 protein coding gene Chr3:56905530-56923457 (+)
C3H/HeJ MGP_C3HHeJ_G0026967
 protein coding gene Chr3:58480042-58497980 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027670
 protein coding gene Chr3:61082846-61102497 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025024
 protein coding gene Chr3:53312975-53331673 (+)
CAST/EiJ MGP_CASTEiJ_G0026419
 protein coding gene Chr3:58660348-58679121 (+)
CBA/J MGP_CBAJ_G0026943
 protein coding gene Chr3:63125855-63143828 (+)
DBA/2J MGP_DBA2J_G0027077
 protein coding gene Chr3:56603220-56621621 (+)
FVB/NJ MGP_FVBNJ_G0027045
 protein coding gene Chr3:55508264-55526080 (+)
LP/J MGP_LPJ_G0027188
 protein coding gene Chr3:59708935-59727782 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0027728
 protein coding gene Chr3:58201792-58219881 (+)
PWK/PhJ MGP_PWKPhJ_G0026151
 protein coding gene Chr3:56230990-56249449 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025964
 protein coding gene Chr3:57808202-57826036 (+)
WSB/EiJ MGP_WSBEiJ_G0026493
 protein coding gene Chr3:58318966-58340949 (+)



Homology
more
  • Human Ortholog
    AADACL2, arylacetamide deacetylase like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AADACL2, arylacetamide deacetylase like 2
  • Links
    NCBI Gene ID: 344752
    neXtProt AC: NX_Q6P093
    UniProt: Q6P093

  • Chr Location
    3q25.1; chr3:151733916-151761339 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 639634 NCBI Gene Model | MGI Sequence Detail 18678 C57BL/6J ±  kb
transcript NM_001128091 RefSeq | MGI Sequence Detail 1590 Not Specified  
polypeptide NP_001121563 RefSeq | MGI Sequence Detail 401 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR029058 Alpha/Beta hydrolase fold
    IPR013094 Alpha/beta hydrolase fold-3
    IPR017157 Arylacetamide deacetylase
    IPR050466 Diverse Carboxylesterases and Gibberellin Receptors
    IPR033140 Lipase, GDXG, putative serine active site
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Diseases 1
    Phenotypes 6
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory