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Lrrc74a Gene Detail
Summary
  • Symbol
    Lrrc74a
  • Name
    leucine rich repeat containing 74A
  • Synonyms
    Gm6772, Lrrc74
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646959
    NCBI Gene: 627607
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:86781143-86810571 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 40.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    937 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646959
 protein coding gene Chr12:86781119-86815799 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019973
 protein coding gene Chr12:87596168-87626250 (+)
A/J MGP_AJ_G0019930
 protein coding gene Chr12:84262926-84292477 (+)
AKR/J MGP_AKRJ_G0019906
 protein coding gene Chr12:86549603-86580497 (+)
BALB/cJ MGP_BALBcJ_G0019910
 protein coding gene Chr12:84605174-84634433 (+)
C3H/HeJ MGP_C3HHeJ_G0019716
 protein coding gene Chr12:87029504-87060421 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020361
 protein coding gene Chr12:90108096-90138790 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017979
 protein coding gene Chr12:81152524-81185422 (+)
CAST/EiJ MGP_CASTEiJ_G0019266
 protein coding gene Chr12:82035036-82065456 (+)
CBA/J MGP_CBAJ_G0019687
 protein coding gene Chr12:93575870-93613705 (+)
DBA/2J MGP_DBA2J_G0019801
 protein coding gene Chr12:83765655-83794684 (+)
FVB/NJ MGP_FVBNJ_G0019788
 protein coding gene Chr12:82745644-82777407 (+)
LP/J MGP_LPJ_G0019875
 protein coding gene Chr12:87469698-87500308 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019827
 protein coding gene Chr12:96338339-96370555 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020394
 protein coding gene Chr12:86174759-86207048 (+)
PWK/PhJ MGP_PWKPhJ_G0019029
 protein coding gene Chr12:78313844-78343231 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018825
 protein coding gene Chr12:80667220-80699408 (+)
WSB/EiJ MGP_WSBEiJ_G0019318
 protein coding gene Chr12:86917928-86947934 (+)



Homology
more
  • Human Ortholog
    LRRC74A, leucine rich repeat containing 74A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC74A, leucine rich repeat containing 74A
  • Synonyms
    C14orf166B, LRRC74
  • Links
    NCBI Gene ID: 145497
    neXtProt AC: NX_Q0VAA2
    UniProt: Q0VAA2

  • Chr Location
    14q24.3; chr14:76826372-76870304 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059114 Ensembl Gene Model | MGI Sequence Detail 29429 C57BL/6J ±  kb
transcript ENSMUST00000223308 Ensembl | MGI Sequence Detail 1854 Not Applicable  
polypeptide ENSMUSP00000152661 Ensembl | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR052394 Leucine-rich repeat-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144854
References
more
  • Summaries
    All 15
    Phenotypes 2
  • Earliest
    J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
  • Latest
    J:157972 Mouse Genome Informatics Scientific Curators, Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). Database Download. 2010;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory