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Slco1a8 Gene Detail
Summary
  • Symbol
    Slco1a8
  • Name
    solute carrier organic anion transporter family, member 1a8
  • Synonyms
    Gm6614
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647159
    NCBI Gene: 625716
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr6:141917571-141957140 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 73.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1209 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647159
 protein coding gene Chr6:141917540-141957989 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031457
 protein coding gene Chr6:146763020-146804374 (-)
A/J MGP_AJ_G0031432
 protein coding gene Chr6:140978537-141019331 (-)
AKR/J MGP_AKRJ_G0031360
 protein coding gene Chr6:145178662-145218139 (-)
BALB/cJ MGP_BALBcJ_G0031439
 protein coding gene Chr6:140768997-140808751 (-)
C3H/HeJ MGP_C3HHeJ_G0031161
 protein coding gene Chr6:145227363-145266763 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031901
 protein coding gene Chr6:150763865-150805381 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030529
 protein coding gene Chr6:144797730-144854567 (-)
CBA/J MGP_CBAJ_G0031121
 protein coding gene Chr6:156507165-156549000 (-)
DBA/2J MGP_DBA2J_G0031278
 protein coding gene Chr6:139781894-139822027 (-)
FVB/NJ MGP_FVBNJ_G0031229
 protein coding gene Chr6:138575691-138614155 (-)
LP/J MGP_LPJ_G0031362
 protein coding gene Chr6:146900200-146939388 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031269
 protein coding gene Chr6:160415715-160456115 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031933
 protein coding gene Chr6:145006306-145047336 (-)
PWK/PhJ MGP_PWKPhJ_G0030256
 protein coding gene Chr6:138297738-138338740 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030080
 protein coding gene Chr6:143222742-143264128 (-)
WSB/EiJ MGP_WSBEiJ_G0030622
 protein coding gene Chr6:145655289-145699757 (-)



Homology
more
  • Human Ortholog
    SLCO1A2, solute carrier organic anion transporter family member 1A2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLCO1A2, solute carrier organic anion transporter family member 1A2
  • Synonyms
    OATP, OATP1A2, OATP-A, SLC21A3
  • Links
    NCBI Gene ID: 6579
    neXtProt AC: NX_P46721
    UniProt: P46721

  • Chr Location
    12p12.1; chr12:21264600-21419634 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079263 Ensembl Gene Model | MGI Sequence Detail 39570 C57BL/6J ±  kb
transcript ENSMUST00000181628 Ensembl | MGI Sequence Detail 2364 Not Applicable  
polypeptide ENSMUSP00000137967 Ensembl | MGI Sequence Detail 670 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
Other
Accession IDs
less
MGI:7516328
References
more
  • Summaries
    All 19
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:163765 van de Steeg E, et al., Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs. J Clin Invest. 2010 Aug 2;120(8):2942-52
  • Latest
    J:334921 Truong JK, et al., Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice. JCI Insight. 2023 Mar 22;8(6)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory