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Lilra5 Gene Detail
Summary
  • Symbol
    Lilra5
  • Name
    leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
  • Synonyms
    Gm4878
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647196
    NCBI Gene: 232801
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4240753-4246462 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    261 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647196
 protein coding gene Chr7:4240643-4246689 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031541
 protein coding gene Chr7:1160516-1166204 (+)
A/J MGP_AJ_G0031515
 protein coding gene Chr7:1150140-1155828 (+)
AKR/J MGP_AKRJ_G0031443
 protein coding gene Chr7:1203215-1208903 (+)
BALB/cJ MGP_BALBcJ_G0031523
 protein coding gene Chr7:1218731-1224419 (+)
C3H/HeJ MGP_C3HHeJ_G0031244
 protein coding gene Chr7:1197006-1202694 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031984
 protein coding gene Chr7:1165125-1170834 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029108
 protein coding gene Chr7:933451-939151 (+)
CAST/EiJ MGP_CASTEiJ_G0030608
 protein coding gene Chr7:1133847-1139541 (+)
CBA/J MGP_CBAJ_G0031202
 protein coding gene Chr7:1383295-1388985 (+)
DBA/2J MGP_DBA2J_G0031361
 protein coding gene Chr7:1120853-1126541 (+)
FVB/NJ MGP_FVBNJ_G0031313
 protein coding gene Chr7:1101978-1107666 (+)
LP/J MGP_LPJ_G0031446
 protein coding gene Chr7:1237104-1242792 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031352
 protein coding gene Chr7:1296046-1301734 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032014
 protein coding gene Chr7:1131806-1137494 (+)
PWK/PhJ MGP_PWKPhJ_G0030336
 protein coding gene Chr7:1307001-1313016 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030161
 protein coding gene Chr7:1257269-1262970 (+)
WSB/EiJ MGP_WSBEiJ_G0030703
 protein coding gene Chr7:1149029-1154718 (+)



Homology
more
  • Human Ortholog
    LILRA5, leukocyte immunoglobulin like receptor A5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LILRA5, leukocyte immunoglobulin like receptor A5
  • Synonyms
    CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9
  • Links
    NCBI Gene ID: 353514
    neXtProt AC: NX_A6NI73
    UniProt: A6NI73

  • Chr Location
    19q13.42; chr19:54307070-54313166 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    6
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070873 Ensembl Gene Model | MGI Sequence Detail 5710 C57BL/6J ±  kb
transcript ENSMUST00000117550 Ensembl | MGI Sequence Detail 2109 Not Applicable  
polypeptide ENSMUSP00000113091 Ensembl | MGI Sequence Detail 295 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR013151 Immunoglobulin
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR050412 Immunoglobulin-like Receptors in Immune Regulation
    IPR003599 Immunoglobulin subtype
Molecular
Reagents
less
  • All nucleic 3
    Genomic 2
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:337210 Shang Y, et al., Leukocyte Immunoglobulin-like Receptor A5 Deletion Aggravates the Pathogenesis of Pseudomonas aeruginosa Keratitis by Promoting Proinflammatory Cytokines. Cornea. 2023 May 1;42(5):607-614
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory