Trav12-3 Gene Detail

Summary

• Symbol
  Trav12-3
• Name
  T cell receptor alpha variable 12-3
• Synonyms
  EG667790, Gm14498

• Feature Type
  gene segment
• IDs
  MGI:3648633
  NCBI Gene: 654836
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:53859209-53859702 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.44 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  207 from dbSNP Build 142
• Strain Annotations
  10

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3648633	gene segment	Chr14:53859114-53859702 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0002547	gene segment	Chr14:47188175-47188756 (+)
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	MGP_C57BL6NJ_G0002651	gene segment	Chr14:49935639-49936227 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0002459	gene segment	Chr14:44260065-44262258 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0002514	gene segment	Chr14:45830779-45831338 (+)
LP/J	MGP_LPJ_G0002559	gene segment	Chr14:48476225-48476824 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0002489	gene segment	Chr14:50799772-50812309 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0002631	gene segment	Chr14:46740118-47474129 (+)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0002370	gene segment	Chr14:43170686-43481779 (-)
WSB/EiJ	MGP_WSBEiJ_G0002446	gene segment	Chr10:32562258-32565382 (+)

Homology

• Human Ortholog
  TRAV18, T cell receptor alpha variable 18

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TRAV18, T cell receptor alpha variable 18
  
• Synonyms
  TCRAV18S1
• Links
  HGNC:12114

  NCBI Gene ID: 28665

  UniProt: A0A075B6X5

  
  
• Chr Location
  14q11.2; chr14:22003106-22003673 (+)  GRCh38

---

• MGI Vertebrate Homology
  Trav12-3 stringent orthology
  1 human;1 mouse;2 zebrafish
  
• HCOP
  vertebrate homology predictions: TRAV18
• Gene Tree
  Trav12-3
  

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  16
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000095958 (Evidence)
• NCBI Gene
  654836

Representative Sequences			Length	Strain/Species
genomic	654836	NCBI Gene Model | MGI Sequence Detail	494	C57BL/6J
polypeptide	A0A075B648	UniProt | EBI | MGI Sequence Detail	115	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain
  IPR051287 T cell receptor variable region

References

• Summaries
  All 6
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Trav12-3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125489	Chr14:53859189-53859201 (+)	-14 bp