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Ces2h Gene Detail
Summary
  • Symbol
    Ces2h
  • Name
    carboxylesterase 2H
  • Synonyms
    Gm5744
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648740
    NCBI Gene: 436059
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105727462-105747042 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    398 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648740
 protein coding gene Chr8:105727462-105747810 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034024
 protein coding gene Chr8:107200089-107212590 (+)
A/J MGP_AJ_G0034005
 protein coding gene Chr8:102983785-102997867 (+)
AKR/J MGP_AKRJ_G0033931
 protein coding gene Chr8:105924529-105938012 (+)
BALB/cJ MGP_BALBcJ_G0033998
 protein coding gene Chr8:103140734-103153209 (+)
C3H/HeJ MGP_C3HHeJ_G0033710
 protein coding gene Chr8:106683139-106695583 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034518
 protein coding gene Chr8:111160072-111172537 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031461
 protein coding gene Chr8:96131198-96143503 (+)
CAST/EiJ MGP_CASTEiJ_G0033037
 protein coding gene Chr8:106166905-106179222 (+)
CBA/J MGP_CBAJ_G0033684
 protein coding gene Chr8:114750043-114764220 (+)
DBA/2J MGP_DBA2J_G0033838
 protein coding gene Chr8:102283625-102296274 (+)
FVB/NJ MGP_FVBNJ_G0033785
 protein coding gene Chr8:101211032-101223692 (+)
LP/J MGP_LPJ_G0033929
 protein coding gene Chr8:107416998-107430036 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033827
 protein coding gene Chr8:117981612-117994954 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034536
 protein coding gene Chr8:105878266-105898645 (+)
PWK/PhJ MGP_PWKPhJ_G0032738
 protein coding gene Chr8:101687295-101700041 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032578
 protein coding gene Chr8:104598896-104613994 (+)
WSB/EiJ MGP_WSBEiJ_G0033152
 protein coding gene Chr8:106561287-106573572 (+)



Homology
more
  • Human Ortholog
    CES2, carboxylesterase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CES2, carboxylesterase 2
  • Synonyms
    CE-2, CES2A1, iCE, PCE-2
  • Links
    NCBI Gene ID: 8824
    neXtProt AC: NX_O00748
    UniProt: O00748

  • Chr Location
    16q22.1; chr16:66934444-66945096 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 436059 NCBI Gene Model | MGI Sequence Detail 19581 C57BL/6J ±  kb
transcript NM_001272045 RefSeq | MGI Sequence Detail 1700 C57BL/6  
polypeptide NP_001258974 RefSeq | MGI Sequence Detail 558 C57BL/6  
For the selected sequence
Protein
Information
less
References
more
  • Summaries
    All 11
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:164863 Holmes RS, et al., Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins. Mamm Genome. 2010 Oct;21(9-10):427-41
  • Latest
    J:335459 Chalhoub G, et al., Carboxylesterase 2a deletion provokes hepatic steatosis and insulin resistance in mice involving impaired diacylglycerol and lysophosphatidylcholine catabolism. Mol Metab. 2023 Jun;72:101725
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory