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Vinac1 Gene Detail
Summary
  • Symbol
    Vinac1
  • Name
    vinculin/alpha-catenin family member 1
  • Synonyms
    Gm14025
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649276
    NCBI Gene: 668894
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr2:128866993-128890092 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 62.63 cM
Strain
Comparison
more
  • SNPs within 2kb
    570 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649276
protein coding gene Chr2:128866061-128907829 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026481
protein coding gene Chr2:132408130-132418122 (-)
A/J MGP_AJ_G0026445
protein coding gene Chr2:127044129-127054143 (-)
AKR/J MGP_AKRJ_G0026420
protein coding gene Chr2:130653643-130663652 (-)
BALB/cJ MGP_BALBcJ_G0026457
protein coding gene Chr2:127304679-127314715 (-)
C3H/HeJ MGP_C3HHeJ_G0026200
protein coding gene Chr2:131159673-131170402 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026902
protein coding gene Chr2:136547475-136557455 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024279
protein coding gene Chr2:121869604-121880518 (-)
CAST/EiJ MGP_CASTEiJ_G0025661
protein coding gene Chr2:131407390-131431805 (-)
CBA/J MGP_CBAJ_G0026180
protein coding gene Chr2:141599655-141609671 (-)
DBA/2J MGP_DBA2J_G0026314
protein coding gene Chr2:126433873-126443926 (-)
FVB/NJ MGP_FVBNJ_G0026278
protein coding gene Chr2:125084001-125093990 (-)
LP/J MGP_LPJ_G0026419
protein coding gene Chr2:132645645-132655661 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026298
protein coding gene Chr2:145516799-145526795 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026957
protein coding gene Chr2:130685848-130695860 (-)
PWK/PhJ MGP_PWKPhJ_G0025397
protein coding gene Chr2:125994650-126028801 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025199
protein coding gene Chr2:129777314-129801437 (-)
WSB/EiJ MGP_WSBEiJ_G0025735
protein coding gene Chr2:131592752-131635297 (-)



Homology
more
  • Human Ortholog
    VINAC1P, vinculin/alpha-catenin family member 1, pseudogene
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VINAC1P, vinculin/alpha-catenin family member 1, pseudogene
  • Links
    NCBI Gene ID: 114515517

  • Chr Location
    2q14.1; chr2:112440396-112440601 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Vinac1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079051 Ensembl Gene Model | MGI Sequence Detail 23100 C57BL/6J ±  kb
transcript ENSMUST00000145798 Ensembl | MGI Sequence Detail 4242 Not Applicable  
polypeptide ENSMUSP00000123404 Ensembl | MGI Sequence Detail 1413 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR036723 Alpha-catenin/vinculin-like superfamily
    IPR006077 Vinculin/alpha-catenin
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2
Other
Accession IDs
less
MGI:6202898
References
more
  • Summaries
    All 16
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory