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Gm12250 Pseudogene Detail
Summary
  • Symbol
    Gm12250
  • Name
    predicted gene 12250
  • Synonyms
    Irgb10
Location &
Maps
more
  • Sequence Map
    Chr11:58078565-58079838 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 35.96 cM
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649299
 pseudogene Chr11:58074669-58081024 (+)
129S1/SvImJ MGP_129S1SvImJ_G0010725
 pseudogene Chr11:57863496-57864769 (+)
A/J MGP_AJ_G0010721
 pseudogene Chr11:55674906-55676179 (+)
AKR/J MGP_AKRJ_G0010679
 pseudogene Chr11:57502110-57503383 (+)
BALB/cJ MGP_BALBcJ_G0010693
 pseudogene Chr11:56014724-56015997 (+)
C3H/HeJ MGP_C3HHeJ_G0010605
 pseudogene Chr11:57435788-57437061 (+)
C57BL/6NJ MGP_C57BL6NJ_G0010968
 pseudogene Chr11:59642503-59643776 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0009599
 pseudogene Chr11:53025131-53026404 (+)
CAST/EiJ MGP_CASTEiJ_G0010428
 pseudogene Chr11:57530877-57532150 (+)
CBA/J MGP_CBAJ_G0010580
 pseudogene Chr11:62391130-62392403 (+)
DBA/2J MGP_DBA2J_G0010618
 pseudogene Chr11:55320537-55321810 (+)
FVB/NJ MGP_FVBNJ_G0010634
 pseudogene Chr11:55016530-55017803 (+)
LP/J MGP_LPJ_G0010705
 pseudogene Chr11:58399885-58401158 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0010608
 pseudogene Chr11:63510545-63511818 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0010941
 pseudogene Chr11:57544727-57546000 (+)
PWK/PhJ MGP_PWKPhJ_G0010323
 pseudogene Chr11:55926296-55927569 (+)
SPRET/EiJ MGP_SPRETEiJ_G0010132
 pseudogene Chr11:57424592-57425865 (+)
WSB/EiJ MGP_WSBEiJ_G0010485
 pseudogene Chr11:57175894-57177167 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Genomic Mutations
    1 involving Gm12250
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    26
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000082292 Ensembl Gene Model | MGI Sequence Detail 1274 C57BL/6J ±  kb
transcript ENSMUST00000119467 Ensembl | MGI Sequence Detail 1274 Not Applicable  
polypeptide Q0GUM3 UniProt | EBI | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • PDB
    7C3K
  • EC
    3.6.5.-
  • InterPro Domains
    IPR051515 Immunity-related GTPase
    IPR007743 Immunity-related GTPases-like
    IPR030385 IRG-type guanine nucleotide-binding (G) domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 26
    Gene Ontology 12
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:333980 Christgen S, et al., The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice. Eur J Immunol. 2022 Feb;52(2):285-296
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory