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Pramel22 Gene Detail
Summary
  • Symbol
    Pramel22
  • Name
    PRAME like 22
  • Synonyms
    Gm13088
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649971
    NCBI Gene: 277668
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:143380330-143387168 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 77.85 cM
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649971
 protein coding gene Chr4:143380330-143387210 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029078
 protein coding gene Chr4:147144036-147146844 (+)
A/J MGP_AJ_G0029045
 protein coding gene Chr4:140768015-140772562 (+)
AKR/J MGP_AKRJ_G0028986
 protein coding gene Chr4:144539885-144543478 (-)
BALB/cJ MGP_BALBcJ_G0029065
 protein coding gene Chr4:141719504-141722997 (-)
C3H/HeJ MGP_C3HHeJ_G0028771
 protein coding gene Chr4:144936694-144941499 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029496
 protein coding gene Chr4:151925715-151927655 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0028202
 protein coding gene Chr4:143463669-143466429 (+)
CBA/J MGP_CBAJ_G0028743
 protein coding gene Chr4:157136215-157141010 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0028850
 protein coding gene Chr4:139997395-140000987 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0029538
 protein coding gene Chr4:145089441-145093047 (-)
PWK/PhJ MGP_PWKPhJ_G0027925
 protein coding gene Chr4:138051205-138054691 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0028281
 protein coding gene Chr4:145375435-145379425 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 277668 NCBI Gene Model | MGI Sequence Detail 6839 C57BL/6J ±  kb
transcript NM_001126325 RefSeq | MGI Sequence Detail 1819 C57BL/6  
polypeptide NP_001119797 RefSeq | MGI Sequence Detail 460 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain superfamily
    IPR026271 PRAME
    IPR050694 PRAME domain-containing protein
Other
Accession IDs
less
MGI:6430519
References
more
  • Summaries
    All 14
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory