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Krtap2-22 Gene Detail
Summary
  • Symbol
    Krtap2-22
  • Name
    keratin associated protein 2-22
  • Synonyms
    Gm11938
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651233
    NCBI Gene: 100041412
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:99493472-99494134 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.95 cM
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651233
 protein coding gene Chr11:99493472-99494134 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019104
 protein coding gene Chr11:102281604-102283375 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0019043
 protein coding gene Chr11:101012420-101013097 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0017130
 protein coding gene Chr11:95532074-95532751 (-)
CAST/EiJ MGP_CASTEiJ_G0018415
 protein coding gene Chr11:102169452-102170490 (-)
CBA/J MGP_CBAJ_G0018831
 protein coding gene Chr11:109812554-109813216 (-)
DBA/2J MGP_DBA2J_G0018939
 protein coding gene Chr11:97549411-97550429 (-)
FVB/NJ MGP_FVBNJ_G0018928
 protein coding gene Chr11:97048028-97048690 (-)
LP/J MGP_LPJ_G0019009
 protein coding gene Chr11:102751117-102753109 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018955
 protein coding gene Chr11:109473916-109476300 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019538
 protein coding gene Chr11:101380008-101380744 (-)
PWK/PhJ MGP_PWKPhJ_G0018186
 protein coding gene Chr11:98615990-98616494 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017975
 protein coding gene Chr11:101145740-101146728 (+)
WSB/EiJ MGP_WSBEiJ_G0018463
 protein coding gene Chr11:101344346-101345008 (-)



Homology
more
  • Human Ortholog
    KRTAP2-2, keratin associated protein 2-2
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP2-2, keratin associated protein 2-2
  • Synonyms
    KAP2.1, KAP2.2, KRTAP2-1, KRTAP2.1A, KRTAP2.1B
  • Links
    NCBI Gene ID: 728279
    neXtProt AC: NX_Q9BYT5, NX_Q9BYU5

  • Chr Location
    17q21.2; chr17:41054498-41055230 (-)  GRCh38
  • Human Ortholog
    KRTAP2-3, keratin associated protein 2-3
  • Synonyms
    KAP2.3, KAP2.4, KRTAP2.3, KRTAP2-4, KRTAP2.4
  • Links
    NCBI Gene ID: 730755
    neXtProt AC: NX_P0C7H8, NX_Q9BYR9
    UniProt: P0C7H8

  • Chr Location
    chr17:41059240-41060114 (-)  GRCh38
  • Human Ortholog
    KRTAP2-4, keratin associated protein 2-4
  • Synonyms
    KAP2.1B, KAP2.3, KAP2.4, KRTAP2-3, KRTAP2.3, KRTAP2.4
  • Links
    NCBI Gene ID: 85294
    neXtProt AC: NX_P0C7H8, NX_Q9BYR9
    UniProt: Q9BYR9

  • Chr Location
    17q21.2; chr17:41065116-41065879 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100041412 NCBI Gene Model | MGI Sequence Detail 663 C57BL/6J ±  kb
transcript NM_001127354 RefSeq | MGI Sequence Detail 663 C57BL/6  
polypeptide NP_001120826 RefSeq | MGI Sequence Detail 131 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
    IPR052154 Keratin-associated protein type 2
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:7580726
References
more
  • Summaries
    All 19
    Phenotypes 6
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory