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Trav1 Gene Detail
Summary
  • Symbol
    Trav1
  • Name
    T cell receptor alpha variable 1
  • Feature Type
    gene segment
  • IDs
    MGI:3651476
    NCBI Gene: 627171
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:52665424-52666333 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 26.94 cM
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651476
 gene segment Chr14:52665385-52666333 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002517
 gene segment Chr14:46496623-46497599 (+)
A/J MGP_AJ_G0002489
 gene segment Chr14:45257885-45258861 (+)
AKR/J MGP_AKRJ_G0002476
 gene segment Chr14:46888113-46889085 (+)
BALB/cJ MGP_BALBcJ_G0002485
 gene segment Chr14:45362793-45363765 (+)
C3H/HeJ MGP_C3HHeJ_G0002461
 gene segment Chr14:46685761-46686733 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002610
 gene segment Chr14:48539742-48540690 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002214
 gene segment Chr14:44447997-44448931 (+)
CAST/EiJ MGP_CASTEiJ_G0002422
 gene segment Chr14:43668069-43669021 (+)
CBA/J MGP_CBAJ_G0002452
 gene segment Chr14:50000189-50001161 (+)
DBA/2J MGP_DBA2J_G0002458
 gene segment Chr14:45031550-45032498 (+)
FVB/NJ MGP_FVBNJ_G0002472
 gene segment Chr14:44606608-44607584 (+)
LP/J MGP_LPJ_G0002513
 gene segment Chr14:47071088-47072064 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002442
 gene segment Chr14:49437669-49438641 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002606
 gene segment Chr14:46262830-46263798 (+)
PWK/PhJ MGP_PWKPhJ_G0002399
 gene segment Chr14:41783752-41784832 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002334
 gene segment Chr14:42322699-42323615 (+)
WSB/EiJ MGP_WSBEiJ_G0002453
 gene segment Chr14:46597539-46598495 (+)



Homology
more
  • Human Ortholog
    TRAV1-1, T cell receptor alpha variable 1-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRAV1-1, T cell receptor alpha variable 1-1
  • Synonyms
    TCRAV1S1, TCRAV7S1, TRAV11
  • Links
    NCBI Gene ID: 28693
    UniProt: A0A0B4J248

  • Chr Location
    14q11.2; chr14:21621838-21622567 (+)  GRCh38
  • Human Ortholog
    TRAV1-2, T cell receptor alpha variable 1-2
  • Synonyms
    TCRAV1S2, TCRAV7S2, TRAV12
  • Links
    NCBI Gene ID: 28692
    UniProt: A0A0B4J238

  • Chr Location
    14q11.2; chr14:21642889-21643586 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 627171 NCBI Gene Model | MGI Sequence Detail 910 C57BL/6J ±  kb
    polypeptide A0A075B5Z4 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR013106 Immunoglobulin V-set domain
    Molecular
    Reagents
    less

    • Microarray probesets 1
    References
    more
    • Summaries
      All 15
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    07/05/2024
    MGI 6.24     		The Jackson Laboratory