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Susd1 Gene Detail
Summary
  • Symbol
    Susd1
  • Name
    sushi domain containing 1
  • Synonyms
    Gm12528
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651543
    NCBI Gene: 634731
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:59314683-59438633 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 32.50 cM
Strain
Comparison
more
  • SNPs within 2kb
    3691 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651543
 protein coding gene Chr4:59314190-59438738 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028335
 protein coding gene Chr4:58211739-58342086 (-)
A/J MGP_AJ_G0028296
 protein coding gene Chr4:55978263-56099881 (-)
AKR/J MGP_AKRJ_G0028245
 protein coding gene Chr4:57542369-57665872 (-)
BALB/cJ MGP_BALBcJ_G0028315
 protein coding gene Chr4:56144437-56273893 (-)
C3H/HeJ MGP_C3HHeJ_G0028036
 protein coding gene Chr4:58079196-58203975 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028756
 protein coding gene Chr4:60253174-60381824 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026062
 protein coding gene Chr4:52708059-52831138 (-)
CAST/EiJ MGP_CASTEiJ_G0027474
 protein coding gene Chr4:57792730-57920443 (-)
CBA/J MGP_CBAJ_G0028001
 protein coding gene Chr4:62290556-62433023 (-)
DBA/2J MGP_DBA2J_G0028151
 protein coding gene Chr4:55876388-56000093 (-)
FVB/NJ MGP_FVBNJ_G0028118
 protein coding gene Chr4:55081941-55206321 (-)
LP/J MGP_LPJ_G0028250
 protein coding gene Chr4:58312138-58434838 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028142
 protein coding gene Chr4:65422882-65550967 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028792
 protein coding gene Chr4:57724169-57851444 (-)
PWK/PhJ MGP_PWKPhJ_G0027199
 protein coding gene Chr4:55909566-56032043 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027027
 protein coding gene Chr4:57048103-57177714 (-)
WSB/EiJ MGP_WSBEiJ_G0027552
 protein coding gene Chr4:57710974-57835198 (-)



Homology
more
  • Human Ortholog
    SUSD1, sushi domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SUSD1, sushi domain containing 1
  • Links
    NCBI Gene ID: 64420
    neXtProt AC: NX_Q6UWL2
    UniProt: Q6UWL2

  • Chr Location
    9q31.3-q32; chr9:112040783-112175297 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038578 Ensembl Gene Model | MGI Sequence Detail 123951 C57BL/6J ±  kb
transcript ENSMUST00000040166 Ensembl | MGI Sequence Detail 3295 Not Applicable  
polypeptide ENSMUSP00000048201 Ensembl | MGI Sequence Detail 752 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR018097 EGF-like calcium-binding, conserved site
    IPR001881 EGF-like calcium-binding domain
    IPR000742 EGF-like domain
    IPR000152 EGF-type aspartate/asparagine hydroxylation site
    IPR009030 Growth factor receptor cysteine-rich domain superfamily
    IPR049883 NOTCH1 EGF-like calcium-binding domain
    IPR051622 Receptor-type Tyrosine-protein Phosphatases
    IPR000436 Sushi/SCR/CCP domain
    IPR035976 Sushi/SCR/CCP superfamily
  • GlyGen
    E9Q3H4 7 sites, 5 N-linked glycans (7 sites)
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory