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Cela3a Gene Detail
Summary
  • Symbol
    Cela3a
  • Name
    chymotrypsin-like elastase family, member 3A
  • Synonyms
    Gm13011
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651647
    NCBI Gene: 242711
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:137128865-137137102 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 69.88 cM
Strain
Comparison
more
  • SNPs within 2kb
    595 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651647
 protein coding gene Chr4:137128865-137137102 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028980
 protein coding gene Chr4:140025691-140034597 (-)
A/J MGP_AJ_G0028939
 protein coding gene Chr4:134075372-134083086 (-)
AKR/J MGP_AKRJ_G0028891
 protein coding gene Chr4:137918951-137926949 (-)
BALB/cJ MGP_BALBcJ_G0028963
 protein coding gene Chr4:134757998-134764482 (-)
C3H/HeJ MGP_C3HHeJ_G0028677
 protein coding gene Chr4:138224466-138235896 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029404
 protein coding gene Chr4:144993862-145008568 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026675
 protein coding gene Chr4:127100625-127109427 (-)
CAST/EiJ MGP_CASTEiJ_G0028109
 protein coding gene Chr4:136375666-136384971 (-)
CBA/J MGP_CBAJ_G0028642
 protein coding gene Chr4:149055397-149067120 (-)
DBA/2J MGP_DBA2J_G0028791
 protein coding gene Chr4:134474542-134483698 (-)
FVB/NJ MGP_FVBNJ_G0028758
 protein coding gene Chr4:133432225-133491900 (-)
LP/J MGP_LPJ_G0028890
 protein coding gene Chr4:140101049-140140174 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028784
 protein coding gene Chr4:153146270-153175826 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029442
 protein coding gene Chr4:138393909-138402142 (-)
PWK/PhJ MGP_PWKPhJ_G0027829
 protein coding gene Chr4:131293798-131300564 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027655
 protein coding gene Chr4:134199890-134208153 (-)
WSB/EiJ MGP_WSBEiJ_G0028187
 protein coding gene Chr4:138566988-138576576 (-)



Homology
more
  • Human Ortholog
    CELA3A, chymotrypsin like elastase 3A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CELA3A, chymotrypsin like elastase 3A
  • Synonyms
    ELA3, ELA3A
  • Links
    NCBI Gene ID: 10136
    neXtProt AC: NX_P09093
    UniProt: P09093

  • Chr Location
    1p36.12; chr1:22001657-22012542 (+)  GRCh38
  • Human Ortholog
    CELA3B, chymotrypsin like elastase 3B
  • Synonyms
    CBPP, ELA3B
  • Links
    NCBI Gene ID: 23436
    neXtProt AC: NX_P08861
    UniProt: P08861

  • Chr Location
    1p36.12; chr1:21977022-21998642 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 242711 NCBI Gene Model | MGI Sequence Detail 8238 C57BL/6J ±  kb
transcript NM_001126318 RefSeq | MGI Sequence Detail 958 C57BL/6  
polypeptide NP_001119790 RefSeq | MGI Sequence Detail 283 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR050850 Peptidase S1 family, Elastase subfamily
    IPR009003 Peptidase S1, PA clan
    IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:356223 Martinez-Ramirez AS, et al., Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development. Gastro Hep Adv. 2022;1(5):807-823
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory