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Pramel31 Gene Detail
Summary
  • Symbol
    Pramel31
  • Name
    PRAME like 31
  • Synonyms
    Gm13119
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651680
    NCBI Gene: 433779
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:144084534-144090989 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 77.98 cM
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651680
 protein coding gene Chr4:144084512-144090989 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029084
 protein coding gene Chr4:147712629-147722319 (+)
A/J MGP_AJ_G0029054
 protein coding gene Chr4:141426469-141445504 (+)
AKR/J MGP_AKRJ_G0029000
 protein coding gene Chr4:145388841-145426083 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0028769
 protein coding gene Chr4:144781778-144870375 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029505
 protein coding gene Chr4:152189642-152192352 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0028750
 protein coding gene Chr4:157450806-157470343 (+)
DBA/2J MGP_DBA2J_G0028890
 protein coding gene Chr4:141201248-141206406 (-)
FVB/NJ MGP_FVBNJ_G0028857
 protein coding gene Chr4:140341326-140347480 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0028877
 protein coding gene Chr4:160059322-160065841 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029550
 protein coding gene Chr4:145870629-145888435 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0027748
 protein coding gene Chr4:140779503-140785180 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PRAMEF1, PRAME family member 1
  • Vertebrate Orthologs
    22
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRAMEF1, PRAME family member 1
  • Links
    NCBI Gene ID: 65121
    neXtProt AC: NX_O95521
    UniProt: O95521

  • Chr Location
    1p36.21; chr1:12791397-12796628 (+)  GRCh38
  • Human Ortholog
    PRAMEF10, PRAME family member 10
  • Links
    NCBI Gene ID: 343071
    neXtProt AC: NX_O60809
    UniProt: O60809

  • Chr Location
    1p36.21; chr1:12892896-12898270 (-)  GRCh38
  • Human Ortholog
    PRAMEF11, PRAME family member 11
  • Links
    NCBI Gene ID: 440560
    neXtProt AC: NX_O60813
    UniProt: O60813

  • Chr Location
    1p36.21; chr1:12824605-12831410 (-)  GRCh38
  • Human Ortholog
    PRAMEF12, PRAME family member 12
  • Links
    NCBI Gene ID: 390999
    neXtProt AC: NX_O95522
    UniProt: O95522

  • Chr Location
    1p36.21; chr1:12773738-12777906 (+)  GRCh38
  • Human Ortholog
    PRAMEF13, PRAME family member 13
  • Links
    NCBI Gene ID: 400736
    neXtProt AC: NX_Q5VWM6
    UniProt: Q5VWM6

  • Chr Location
    1p36.21; chr1:13196188-13201409 (-)  GRCh38
  • Human Ortholog
    PRAMEF18, PRAME family member 18
  • Links
    NCBI Gene ID: 391003
    neXtProt AC: NX_Q5VWM3
    UniProt: Q5VWM3

  • Chr Location
    1p36.21; chr1:13222695-13226154 (-)  GRCh38
  • Human Ortholog
    PRAMEF19, PRAME family member 19
  • Links
    NCBI Gene ID: 645414
    neXtProt AC: NX_Q5SWL8
    UniProt: Q5SWL8

  • Chr Location
    1p36.21; chr1:13368431-13371947 (-)  GRCh38
  • Human Ortholog
    PRAMEF2, PRAME family member 2
  • Synonyms
    DJ845O24.3
  • Links
    NCBI Gene ID: 65122
    neXtProt AC: NX_O60811
    UniProt: O60811

  • Chr Location
    1p36.21; chr1:12857086-12861909 (+)  GRCh38
  • Human Ortholog
    PRAMEF20, PRAME family member 20
  • Synonyms
    PRAMEF21
  • Links
    NCBI Gene ID: 645425
    neXtProt AC: NX_Q5VT98
    UniProt: Q5VT98

  • Chr Location
    1p36.21; chr1:13410450-13421328 (+)  GRCh38
  • Human Ortholog
    PRAMEF25, PRAME family member 25
  • Links
    NCBI Gene ID: 441873
    neXtProt AC: NX_A6NGN4
    UniProt: A6NGN4

  • Chr Location
    1p36.21; chr1:13068677-13077884 (+)  GRCh38
  • Human Ortholog
    PRAMEF26, PRAME family member 26
  • Synonyms
    PRAMEF25
  • Links
    NCBI Gene ID: 645359
    neXtProt AC: NX_A6NGN4
    UniProt: H0Y7S4

  • Chr Location
    1p36.21
  • Human Ortholog
    PRAMEF27, PRAME family member 27
  • Links
    NCBI Gene ID: 101929983
    neXtProt AC: NX_A3QJZ7
    UniProt: A3QJZ7

  • Chr Location
    chr1:13049476-13056575 (-)  GRCh38
  • Human Ortholog
    PRAMEF33, PRAME family member 33
  • Synonyms
    PRAMEF33P
  • Links
    NCBI Gene ID: 645382
    neXtProt AC: NX_A0A0G2JMD5
    UniProt: A0A0G2JMD5

  • Chr Location
    1p36.21; chr1:13303539-13308907 (+)  GRCh38
  • Human Ortholog
    PRAMEF4, PRAME family member 4
  • Links
    NCBI Gene ID: 400735
    neXtProt AC: NX_O60810
    UniProt: O60810

  • Chr Location
    1p36.21; chr1:12879212-12886201 (-)  GRCh38
  • Human Ortholog
    PRAMEF5, PRAME family member 5
  • Synonyms
    PRAMEF23, PRAMEF5L
  • Links
    NCBI Gene ID: 343068
    neXtProt AC: NX_Q5TYX0
    UniProt: Q5TYX0

  • Chr Location
    1p36.21; chr1:13254198-13263435 (+)  GRCh38
  • Human Ortholog
    PRAMEF6, PRAME family member 6
  • Links
    NCBI Gene ID: 440561
    neXtProt AC: NX_Q5VXH4
    UniProt: Q5VXH4

  • Chr Location
    1p36.21; chr1:12938472-12947580 (-)  GRCh38
  • Human Ortholog
    PRAMEF7, PRAME family member 7
  • Links
    NCBI Gene ID: 441871
    neXtProt AC: NX_Q5VXH5
    UniProt: Q5VXH5

  • Chr Location
    1p36.21; chr1:12916610-12920751 (+)  GRCh38
  • Human Ortholog
    PRAMEF8, PRAME family member 8
  • Synonyms
    PRAMEF24
  • Links
    NCBI Gene ID: 391002
    neXtProt AC: NX_Q5VWM4
    UniProt: Q5VWM4

  • Chr Location
    1p36.21; chr1:13281304-13285137 (-)  GRCh38
  • Human Ortholog
    PRAMEF9, PRAME family member 9
  • Links
    NCBI Gene ID: 343070
    UniProt: P0DUQ2

  • Chr Location
    1p36.21; chr1:13171848-13179459 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PRAME associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 433779 NCBI Gene Model | MGI Sequence Detail 6456 C57BL/6J ±  kb
transcript NM_001034101 RefSeq | MGI Sequence Detail 2072 Not Specified  
polypeptide NP_001029273 RefSeq | MGI Sequence Detail 481 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain superfamily
    IPR026271 PRAME
    IPR050694 PRAME domain-containing protein
Molecular
Reagents
less
  • All nucleic 3
    Genomic 2
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:6430528
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory