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Wfdc11 Gene Detail
Summary
  • Symbol
    Wfdc11
  • Name
    WAP four-disulfide core domain 11
  • Synonyms
    OTTMUSG00000016290
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651686
    NCBI Gene: 629761
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164504814-164516007 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.24 cM
Strain
Comparison
more
  • SNPs within 2kb
    559 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651686
 protein coding gene Chr2:164504814-164516011 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026865
 protein coding gene Chr2:170145080-170157288 (-)
A/J MGP_AJ_G0026832
 protein coding gene Chr2:163197959-163209256 (-)
AKR/J MGP_AKRJ_G0026803
 protein coding gene Chr2:168047608-168058710 (-)
BALB/cJ MGP_BALBcJ_G0026841
 protein coding gene Chr2:163558380-163569234 (-)
C3H/HeJ MGP_C3HHeJ_G0026583
 protein coding gene Chr2:168408804-168420750 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027288
 protein coding gene Chr2:175074147-175087883 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024659
 protein coding gene Chr2:156610027-156622527 (-)
CAST/EiJ MGP_CASTEiJ_G0026041
 protein coding gene Chr2:168825863-168838003 (-)
CBA/J MGP_CBAJ_G0026560
 protein coding gene Chr2:181427613-181444274 (-)
DBA/2J MGP_DBA2J_G0026698
 protein coding gene Chr2:162365889-162377077 (-)
FVB/NJ MGP_FVBNJ_G0026664
 protein coding gene Chr2:160786016-160797721 (-)
LP/J MGP_LPJ_G0026800
 protein coding gene Chr2:170215389-170226529 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026683
 protein coding gene Chr2:184983811-184996843 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027345
 protein coding gene Chr2:167950570-167963628 (-)
PWK/PhJ MGP_PWKPhJ_G0025778
 protein coding gene Chr2:161964413-161975987 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025579
 protein coding gene Chr2:166857071-166869325 (-)
WSB/EiJ MGP_WSBEiJ_G0026114
 protein coding gene Chr2:168833306-168844233 (-)



Homology
more
  • Human Ortholog
    WFDC11, WAP four-disulfide core domain 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WFDC11, WAP four-disulfide core domain 11
  • Synonyms
    WAP11
  • Links
    NCBI Gene ID: 259239
    neXtProt AC: NX_Q8NEX6
    UniProt: Q8NEX6

  • Chr Location
    20q13.12; chr20:45648563-45670270 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078940 Ensembl Gene Model | MGI Sequence Detail 11194 C57BL/6J ±  kb
transcript ENSMUST00000109332 Ensembl | MGI Sequence Detail 617 Not Applicable  
polypeptide ENSMUSP00000104956 Ensembl | MGI Sequence Detail 82 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 16
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
  • Latest
    J:300068 Andrade AD, et al., Lipopolysaccharide-induced epididymitis modifies the transcriptional profile of Wfdc genes in mice. Biol Reprod. 2021 Jan 4;104(1):144-158
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory