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Tmem235 Gene Detail
Summary
  • Symbol
    Tmem235
  • Name
    transmembrane protein 235
  • Synonyms
    Cldn27, Gm12581, Tmem235
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651706
    NCBI Gene: 546519
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr11:117751578-117756369 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 82.96 cM
Strain
Comparison
more
  • SNPs within 2kb
    220 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651706
protein coding gene Chr11:117751578-117756369 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019457
protein coding gene Chr11:122145666-122152453 (+)
A/J MGP_AJ_G0019425
protein coding gene Chr11:116734614-116739424 (+)
AKR/J MGP_AKRJ_G0019395
protein coding gene Chr11:120286952-120291742 (+)
BALB/cJ MGP_BALBcJ_G0019400
protein coding gene Chr11:117103888-117109271 (+)
C3H/HeJ MGP_C3HHeJ_G0019206
protein coding gene Chr11:120574400-120580272 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019849
protein coding gene Chr11:125873905-125878549 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017474
protein coding gene Chr11:113739778-113745166 (+)
CAST/EiJ MGP_CASTEiJ_G0018760
protein coding gene Chr11:121993898-121999658 (+)
CBA/J MGP_CBAJ_G0019177
protein coding gene Chr11:130826642-130831434 (+)
DBA/2J MGP_DBA2J_G0019289
protein coding gene Chr11:116134391-116139238 (+)
FVB/NJ MGP_FVBNJ_G0019281
protein coding gene Chr11:115753700-115758892 (+)
LP/J MGP_LPJ_G0019359
protein coding gene Chr11:122471520-122476189 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019314
protein coding gene Chr11:129787651-129794236 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019888
protein coding gene Chr11:120937481-120942267 (+)
PWK/PhJ MGP_PWKPhJ_G0018526
protein coding gene Chr11:117492429-117497204 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018318
protein coding gene Chr11:120665973-120670755 (+)
WSB/EiJ MGP_WSBEiJ_G0018812
protein coding gene Chr11:120902791-120907579 (+)



Homology
more
  • Human Ortholog
    TMEM235, transmembrane protein 235
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM235, transmembrane protein 235
  • Synonyms
    ARGM1
  • Links
    NCBI Gene ID: 283999
    neXtProt AC: NX_A6NFC5
    UniProt: A6NFC5

  • Chr Location
    17q25.3; chr17:78231293-78240987 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 546519 NCBI Gene Model | MGI Sequence Detail 4792 C57BL/6J ±  kb
transcript NM_001085535 RefSeq | MGI Sequence Detail 1820 Not Specified  
polypeptide B1AQL3 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:169091 Mineta K, et al., Predicted expansion of the claudin multigene family. FEBS Lett. 2011 Feb 18;585(4):606-12
  • Latest
    J:174211 Maher GJ, et al., The cataract-associated protein TMEM114, and TMEM235, are glycosylated transmembrane proteins that are distinct from claudin family members. FEBS Lett. 2011 Jul 21;585(14):2187-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory