Zfp442 MGI Mouse Gene Detail - MGI:3651999

Zfp442 Gene Detail

Symbol

Zfp442
Name

zinc finger protein 442
Synonyms

OTTMUSG00000015730

Feature Type

protein coding gene
IDs

MGI:3651999
NCBI Gene: 668923
Alliance

gene page

Sequence Map

Chr2:150249061-150293406 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 74.43 cM

SNPs within 2kb

576 from dbSNP Build 142
Strain Annotations

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3651999	protein coding gene	Chr2:150244400-150293421 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

ZNF234, zinc finger protein 234

Vertebrate Orthologs

13

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF234, zinc finger protein 234
Synonyms

HZF4, ZNF269
Links

HGNC:13027

NCBI Gene ID: 10780

neXtProt AC: NX_Q14588

UniProt: Q14588
Chr Location

19q13.31; chr19:44141554-44160313 (+) GRCh38

Human Ortholog

ZNF254, zinc finger protein 254
Synonyms

BMZF-5, HD-ZNF1, ZNF539, ZNF91L
Links

HGNC:13047

NCBI Gene ID: 9534

neXtProt AC: NX_O75437

UniProt: O75437
Chr Location

19p12; chr19:24033405-24129968 (+) GRCh38

Human Ortholog

ZNF28, zinc finger protein 28
Synonyms

KOX24
Links

HGNC:13073

NCBI Gene ID: 7576

neXtProt AC: NX_P17035

UniProt: P17035
Chr Location

19q13.41; chr19:52797408-52857600 (-) GRCh38

Human Ortholog

ZNF432, zinc finger protein 432
Links

HGNC:20810

NCBI Gene ID: 9668

neXtProt AC: NX_O94892

UniProt: O94892
Chr Location

19q13.41; chr19:52031378-52095738 (-) GRCh38

Human Ortholog

ZNF493, zinc finger protein 493
Links

HGNC:23708

NCBI Gene ID: 284443

neXtProt AC: NX_Q6ZR52

UniProt: Q6ZR52
Chr Location

19p12; chr19:21397119-21427577 (+) GRCh38

Human Ortholog

ZNF595, zinc finger protein 595
Links

HGNC:27196

NCBI Gene ID: 152687

neXtProt AC: NX_Q8IYB9

UniProt: Q8IYB9
Chr Location

4p16.3; chr4:53286-88208 (+) GRCh38

Human Ortholog

ZNF611, zinc finger protein 611
Links

HGNC:28766

NCBI Gene ID: 81856

neXtProt AC: NX_Q8N823

UniProt: Q8N823
Chr Location

19q13.41; chr19:52702813-52735073 (-) GRCh38

Human Ortholog

ZNF615, zinc finger protein 615
Links

HGNC:24740

NCBI Gene ID: 284370

neXtProt AC: NX_Q8N8J6

UniProt: Q8N8J6
Chr Location

19q13.41; chr19:51991332-52008230 (-) GRCh38

Human Ortholog

ZNF676, zinc finger protein 676
Links

HGNC:20429

NCBI Gene ID: 163223

neXtProt AC: NX_Q8N7Q3

UniProt: Q8N7Q3
Chr Location

19p12; chr19:22179089-22260304 (-) GRCh38

Human Ortholog

ZNF726, zinc finger protein 726
Synonyms

ZNF92P3
Links

HGNC:32462

NCBI Gene ID: 730087

neXtProt AC: NX_A6NNF4

UniProt: A6NNF4
Chr Location

19p12

Human Ortholog

ZNF728, zinc finger protein 728
Links

HGNC:32463

NCBI Gene ID: 388523

neXtProt AC: NX_P0DKX0

UniProt: P0DKX0
Chr Location

19p12

Human Ortholog

ZNF732, zinc finger protein 732
Links

HGNC:37138

NCBI Gene ID: 654254

neXtProt AC: NX_B4DXR9

UniProt: B4DXR9
Chr Location

4p16.3; chr4:270675-305474 (-) GRCh38

Human Ortholog

ZNF93, zinc finger protein 93
Synonyms

HPF34, HTF34, TF34, ZNF505
Links

HGNC:13169

NCBI Gene ID: 81931

neXtProt AC: NX_P35789

UniProt: P35789
Chr Location

19p12

MGI Vertebrate Homology

Zfp442 stringent orthology
13 human;1 mouse
HCOP

vertebrate homology predictions: ZNF234, ZNF254, ZNF28, ZNF432, ZNF493, ZNF595, ZNF611, ZNF615, ZNF676, ZNF726, ZNF728, ZNF732, ZNF93
Gene Tree

Zfp442

less

Phenotype Summary

5 phenotype references

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

4
Radiation induced

1
Genomic Mutations

2 involving Zfp442
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

48 strains or lines available

less

All GO Annotations

9
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

4

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

less

All Sequences

15
RefSeq

6
UniProt

2
CCDS

CCDS79853.1

Ensembl

ENSMUSG00000068130 (Evidence)
NCBI Gene

668923

			Length	Strain/Species	Flank
genomic	ENSMUSG00000068130	Ensembl Gene Model \| MGI Sequence Detail	44346	C57BL/6J	± kb
transcript	ENSMUST00000109916	Ensembl \| MGI Sequence Detail	2922	Not Applicable
polypeptide	ENSMUSP00000105542	Ensembl \| MGI Sequence Detail	667	Not Applicable

less

UniProt

2 Sequences
InterPro Domains

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR050169 Krueppel C2H2-type zinc-finger

IPR050826 Krueppel C2H2-type Zinc Finger

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

less

All nucleic 4

cDNA 4

Microarray probesets 2

Summaries

All 17

Gene Ontology 2

Phenotypes 5
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24