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Kcng2 Gene Detail
Summary
  • Symbol
    Kcng2
  • Name
    potassium voltage-gated channel, subfamily G, member 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3694646
    NCBI Gene: 240444
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80337761-80407469 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 53.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2277 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3694646
 protein coding gene Chr18:80337731-80407469 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024595
 protein coding gene Chr18:81208718-81290236 (-)
A/J MGP_AJ_G0024562
 protein coding gene Chr18:77650813-77724478 (-)
AKR/J MGP_AKRJ_G0024533
 protein coding gene Chr18:79982972-80055866 (-)
BALB/cJ MGP_BALBcJ_G0024560
 protein coding gene Chr18:77836416-77907520 (-)
C3H/HeJ MGP_C3HHeJ_G0024329
 protein coding gene Chr18:80062536-80137351 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025007
 protein coding gene Chr18:83293731-83371438 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022438
 protein coding gene Chr18:76507823-76583180 (-)
CAST/EiJ MGP_CASTEiJ_G0023802
 protein coding gene Chr18:80394526-80469060 (-)
CBA/J MGP_CBAJ_G0024299
 protein coding gene Chr18:86337918-86415574 (-)
DBA/2J MGP_DBA2J_G0024429
 protein coding gene Chr18:77200835-77271337 (-)
FVB/NJ MGP_FVBNJ_G0024395
 protein coding gene Chr18:76521005-76591576 (-)
LP/J MGP_LPJ_G0024513
 protein coding gene Chr18:81078244-81152368 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024425
 protein coding gene Chr18:87586983-87661926 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025056
 protein coding gene Chr18:80117838-80195295 (-)
PWK/PhJ MGP_PWKPhJ_G0023547
 protein coding gene Chr18:77602076-77674695 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023353
 protein coding gene Chr18:80299302-80376875 (-)
WSB/EiJ MGP_WSBEiJ_G0023864
 protein coding gene Chr18:80072920-80145608 (-)



Homology
more
  • Human Ortholog
    KCNG2, potassium voltage-gated channel modifier subfamily G member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCNG2, potassium voltage-gated channel modifier subfamily G member 2
  • Synonyms
    KCNF2, KV6.2
  • Links
    NCBI Gene ID: 26251
    neXtProt AC: NX_Q9UJ96
    UniProt: Q9UJ96

  • Chr Location
    18q23; chr18:79797938-79900184 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000059852 Ensembl Gene Model | MGI Sequence Detail 69709 C57BL/6J ±  kb
    transcript ENSMUST00000077962 Ensembl | MGI Sequence Detail 2813 Not Applicable  
    polypeptide ENSMUSP00000077112 Ensembl | MGI Sequence Detail 480 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR000210 BTB/POZ domain
      IPR005821 Ion transport domain
      IPR003131 Potassium channel tetramerisation-type BTB domain
      IPR003968 Potassium channel, voltage dependent, Kv
      IPR003969 Potassium channel, voltage dependent, Kv6
      IPR011333 SKP1/BTB/POZ domain superfamily
      IPR027359 Voltage-dependent channel domain superfamily
      IPR028325 Voltage-gated potassium channel
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3034694
    References
    more
    • Summaries
      All 21
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory