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Mroh2a Gene Detail
Summary
  • Symbol
    Mroh2a
  • Name
    maestro heat-like repeat family member 2A
  • Synonyms
    ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804
  • Feature Type
    protein coding gene
  • IDs
    MGI:3705228
    NCBI Gene: 100040766
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88154713-88190011 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 44.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1150 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3705228
 protein coding gene Chr1:88154708-88190011 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0016049
 protein coding gene Chr1:89197826-89206578 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014397
 protein coding gene Chr1:80715984-80748970 (+)
CAST/EiJ MGP_CASTEiJ_G0015635
 protein coding gene Chr1:88443875-88454944 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0016152
 protein coding gene Chr1:99460140-99461830 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016719
 protein coding gene Chr1:88963163-89017760 (+)
PWK/PhJ MGP_PWKPhJ_G0015419
 protein coding gene Chr1:85016943-85023985 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015201
 protein coding gene Chr1:87884141-87920351 (+)
WSB/EiJ MGP_WSBEiJ_G0015692
 protein coding gene Chr1:88644929-88656411 (+)



Homology
more
  • Human Ortholog
    MROH2A, maestro heat like repeat family member 2A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH2A, maestro heat like repeat family member 2A
  • Synonyms
    HEATR7B1
  • Links
    NCBI Gene ID: 339766
    UniProt: A6NES4

  • Chr Location
    2q37.1; chr2:233775679-233833423 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Mroh2a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    109 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100040766 NCBI Gene Model | MGI Sequence Detail 35299 C57BL/6J ±  kb
transcript NM_001281466 RefSeq | MGI Sequence Detail 7502 C57BL/6  
polypeptide NP_001268395 RefSeq | MGI Sequence Detail 1671 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
Other
Accession IDs
less
MGI:3704192
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:267911 Timmermans S, et al., Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. JCI Insight. 2018 Jul 12;3(13)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory