Defa-ps16 Pseudogene Detail

Summary

• Symbol
  Defa-ps16
• Name
  defensin, alpha, pseudogene 16

• Feature Type
  pseudogene
• IDs
  MGI:3705774
  NCBI Gene: 100040668
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr8:21832602-21832772 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 10.35 cM

Strain
Comparison

• SNPs within 2kb
  34 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3705774	pseudogene	Chr8:21832587-21832788 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Defa-ps16
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Defa-ps16
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  5
• RefSeq
  1

• Ensembl
  ENSMUSG00000082918 (Evidence)
• NCBI Gene
  100040668

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000082918	Ensembl Gene Model | MGI Sequence Detail	171	C57BL/6J
transcript	ENSMUST00000121939	Ensembl | MGI Sequence Detail	171	Not Applicable

References

• Summaries
  All 6

  Phenotypes 1
• Earliest
  J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662