Defa-ps15 Pseudogene Detail

Summary

• Symbol
  Defa-ps15
• Name
  defensin, alpha, pseudogene 15
• Synonyms
  OTTMUSG00000020718

• Feature Type
  pseudogene
• IDs
  MGI:3705808
  NCBI Gene: 100040528
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr8:19522909-19524748 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 10.35 cM

Strain
Comparison

• SNPs within 2kb
  384 from dbSNP Build 142
• Strain Annotations
  16

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3705808	pseudogene	Chr8:19522909-19524748 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0040663	pseudogene	Chr8:17011251-17013130 (-)
A/J	MGP_AJ_G0040662	pseudogene	Chr8:16461385-16463264 (-)
AKR/J	MGP_AKRJ_G0040589	pseudogene	Chr8:16980903-16982742 (-)
BALB/cJ	MGP_BALBcJ_G0040653	pseudogene	Chr8:16557055-16558934 (-)
C3H/HeJ	MGP_C3HHeJ_G0040291	pseudogene	Chr8:17209427-17211306 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0041348	pseudogene	Chr8:17505996-17507835 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0039330	pseudogene	Chr8:16980180-16982019 (-)
CBA/J	MGP_CBAJ_G0040256	pseudogene	Chr8:18405361-18407240 (-)
DBA/2J	MGP_DBA2J_G0040469	pseudogene	Chr8:16349076-16350955 (-)
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0040505	pseudogene	Chr8:17013615-17015454 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0040393	pseudogene	Chr8:18526552-18528433 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0041394	pseudogene	Chr8:16916208-16918047 (-)
PWK/PhJ	MGP_PWKPhJ_G0038381	pseudogene	Chr11:44246884-44248705 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0038696	pseudogene	Chr8:16861025-16862911 (-)
WSB/EiJ	MGP_WSBEiJ_G0039580	pseudogene	Chr8:16987403-16989242 (-)

Homology

• Gene Tree
  Defa-ps15
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Defa-ps15
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  20
• RefSeq
  1

• Ensembl
  ENSMUSG00000080894 (Evidence)
• NCBI Gene
  100040528

Representative Sequences			Length	Strain/Species
genomic	100040528	NCBI Gene Model | MGI Sequence Detail	1840	C57BL/6J

References

• Summaries
  All 6

  Phenotypes 1
• Earliest
  J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662