Defa-ps14 Pseudogene Detail

Summary

• Symbol
  Defa-ps14
• Name
  defensin, alpha, pseudogene 14
• Synonyms
  OTTMUSG00000020719

• Feature Type
  pseudogene
• IDs
  MGI:3705817
  NCBI Gene: 100040514
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr8:19472522-19473460 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 10.35 cM

Strain
Comparison

• SNPs within 2kb
  181 from dbSNP Build 142
• Strain Annotations
  13

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3705817	pseudogene	Chr8:19472522-19473460 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0040662	pseudogene	Chr8:16852872-16853822 (-)
A/J	MGP_AJ_G0040660	pseudogene	Chr8:16400662-16401600 (+)
AKR/J	MGP_AKRJ_G0040588	pseudogene	Chr8:16886244-16887182 (+)
BALB/cJ	MGP_BALBcJ_G0040651	pseudogene	Chr8:16489989-16490927 (+)
C3H/HeJ	MGP_C3HHeJ_G0040290	pseudogene	Chr8:17132554-17133492 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0041347	pseudogene	Chr8:17448060-17448998 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0039329	pseudogene	Chr8:16819046-16849311 (-)
CBA/J	MGP_CBAJ_G0040255	pseudogene	Chr8:18320412-18321350 (+)
DBA/2J	MGP_DBA2J_G0040468	pseudogene	Chr8:16293705-16294643 (+)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	MGP_NODShiLtJ_G0040390	pseudogene	Chr8:18456354-18457292 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0041393	pseudogene	Chr8:16838698-16839636 (+)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0038693	pseudogene	Chr8:16604398-16605359 (-)
WSB/EiJ	no annotation

Homology

• Gene Tree
  Defa-ps14
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Defa-ps14
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  17
• RefSeq
  1

• Ensembl
  ENSMUSG00000082710 (Evidence)
• NCBI Gene
  100040514

Representative Sequences			Length	Strain/Species
genomic	100040514	NCBI Gene Model | MGI Sequence Detail	939	C57BL/6J

References

• Summaries
  All 6

  Phenotypes 1
• Earliest
  J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662