Hmtb8 QTL Detail

Summary

• Symbol
  Hmtb8
• Name
  hemostasis and thrombosis rebleeding time 8

• Feature Type
  QTL
• IDs
  MGI:3708976
• Candidate Genes
  1 Gene

Location &
Maps

• Sequence Map
  Chr17:57534447-57534623 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 2
• Earliest
  J:139651 Sa Q, et al., Quantitative trait locus analysis for hemostasis and thrombosis. Mamm Genome. 2008 Jun;19(6):406-12
• Latest
  J:163239 Sa Q, et al., Mouse chromosome 17 candidate modifier genes for thrombosis. Mamm Genome. 2010 Aug;21(7-8):337-49

Candidate Genes for Hmtb8:

Gene	Genome Location (GRCm39)	Reference	QTL Note
Emilin2	Chr17:71559167-71618551 (-)	J:163239	The authors identified nine candidate genes on mouse Chromosome 17 that potentially code for thrombosis susceptibility QTLs Hmbt8 and Hmbt9. Emilin2 proved to be a promising candidate but further investigation is required.