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Krtap4-21 Gene Detail
Summary
  • Symbol
    Krtap4-21
  • Name
    keratin associated protein 4-21
  • Synonyms
    Gm11569
  • Feature Type
    protein coding gene
  • IDs
    MGI:3709346
    NCBI Gene: 670472
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:99688890-99689758 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.14 cM
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3709346
 protein coding gene Chr11:99688890-99689758 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019119
 protein coding gene Chr11:102502669-102503582 (-)
A/J MGP_AJ_G0019088
 protein coding gene Chr11:98173585-98174483 (-)
AKR/J MGP_AKRJ_G0019059
 protein coding gene Chr11:101236929-101241774 (-)
BALB/cJ MGP_BALBcJ_G0019060
 protein coding gene Chr11:98733823-98734736 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0019510
 protein coding gene Chr11:105626304-105627718 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0018953
 protein coding gene Chr11:97753407-97754971 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0019024
 protein coding gene Chr11:103047268-103049421 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018971
 protein coding gene Chr11:109714936-109715834 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Synonyms
    KAP4.3
  • Links
    NCBI Gene ID: 85290
    neXtProt AC: NX_Q9BYR4
    UniProt: Q9BYR4

  • Chr Location
    17q21.2; chr17:41167231-41168221 (-)  GRCh38
  • Human Ortholog
    KRTAP4-9, keratin associated protein 4-9
  • Synonyms
    KAP4.9
  • Links
    NCBI Gene ID: 100132386
    neXtProt AC: NX_Q9BYQ8
    UniProt: Q9BYQ8

  • Chr Location
    17q21.2; chr17:41105389-41106488 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 670472 NCBI Gene Model | MGI Sequence Detail 869 C57BL/6J ±  kb
transcript NM_001099312 RefSeq | MGI Sequence Detail 869 Not Specified  
polypeptide NP_001092782 RefSeq | MGI Sequence Detail 180 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
Other
Accession IDs
less
MGI:7580862
References
more
  • Summaries
    All 14
    Phenotypes 6
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory