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Parp10 Gene Detail
Summary
  • Symbol
    Parp10
  • Name
    poly (ADP-ribose) polymerase family, member 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:3712326
    NCBI Gene: 671535
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76117195-76127640 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.57 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    352 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3712326
 protein coding gene Chr15:76115374-76127641 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021978
 protein coding gene Chr15:76294698-76306982 (-)
A/J MGP_AJ_G0021936
 protein coding gene Chr15:73516019-73530016 (-)
AKR/J MGP_AKRJ_G0021919
 protein coding gene Chr15:75510338-75523227 (-)
BALB/cJ MGP_BALBcJ_G0021945
 protein coding gene Chr15:73538973-73551882 (-)
C3H/HeJ MGP_C3HHeJ_G0021717
 protein coding gene Chr15:75557182-75569489 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022385
 protein coding gene Chr15:79141824-79159904 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019914
 protein coding gene Chr15:70179780-70192203 (-)
CAST/EiJ MGP_CASTEiJ_G0021236
 protein coding gene Chr15:76356855-76371661 (-)
CBA/J MGP_CBAJ_G0021684
 protein coding gene Chr15:81645356-81659319 (-)
DBA/2J MGP_DBA2J_G0021809
 protein coding gene Chr15:73055421-73067704 (-)
FVB/NJ MGP_FVBNJ_G0021790
 protein coding gene Chr15:72101743-72114002 (-)
LP/J MGP_LPJ_G0021880
 protein coding gene Chr15:76385488-76400173 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021814
 protein coding gene Chr15:86963657-86975891 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022405
 protein coding gene Chr15:75754289-75766577 (-)
PWK/PhJ MGP_PWKPhJ_G0020977
 protein coding gene Chr15:73200512-73212901 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020817
 protein coding gene Chr15:75476025-75488481 (-)
WSB/EiJ MGP_WSBEiJ_G0021288
 protein coding gene Chr15:75844804-75858981 (-)



Homology
more
  • Human Ortholog
    PARP10, poly(ADP-ribose) polymerase family member 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARP10, poly(ADP-ribose) polymerase family member 10
  • Synonyms
    ARTD10
  • Links
    NCBI Gene ID: 84875
    neXtProt AC: NX_Q53GL7
    UniProt: Q53GL7

  • Chr Location
    8q24.3; chr8:143977153-144012772 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    42
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 671535 NCBI Gene Model | MGI Sequence Detail 10446 C57BL/6J ±  kb
transcript NM_001163576 RefSeq | MGI Sequence Detail 3411 C57BL/6  
polypeptide Q8CIE4 UniProt | EBI | MGI Sequence Detail 960 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000012290 protein mono-ADP-ribosyltransferase PARP10
    (term hierarchy)
  • EC
    2.4.2.-
  • InterPro Domains
    IPR052056 Mono-ADP-ribosyltransferase ARTD/PARP
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR034464 PARP-10, RNA recognition motif 1 and 2
    IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
  • GlyGen
    Q8CIE4 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 48
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:310115 Gao XQ, et al., The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N(6)-methyladenosine methylation of Parp10 mRNA. Nat Cell Biol. 2020 Nov;22(11):1319-1331
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory