Mir190b MGI Mouse Gene Detail - MGI:3718457

Symbol

Mir190b
Name

microRNA 190b
Synonyms

Mirn190b, mmu-mir-190b

Feature Type

miRNA gene
IDs

MGI:3718457
NCBI Gene: 100124481
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr3:89977327-89977406 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 39.20 cM
Mapping Data

1 experiment

SNPs within 2kb

72 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3718457	miRNA gene	Chr3:89977327-89977406 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008660	miRNA gene	Chr3:90336052-90336131 (+)
A/J	MGP_AJ_G0008650	miRNA gene	Chr3:87341214-87341293 (+)
AKR/J	MGP_AKRJ_G0008640	miRNA gene	Chr3:89478487-89478566 (+)
BALB/cJ	MGP_BALBcJ_G0008638	miRNA gene	Chr3:87308309-87308388 (+)
C3H/HeJ	MGP_C3HHeJ_G0008578	miRNA gene	Chr3:89652605-89652684 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008851	miRNA gene	Chr3:93723934-93724013 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007818	miRNA gene	Chr3:82836358-82836437 (+)
CAST/EiJ	MGP_CASTEiJ_G0008431	miRNA gene	Chr3:90024078-90024157 (+)
CBA/J	MGP_CBAJ_G0008542	miRNA gene	Chr3:96970146-96970225 (+)
DBA/2J	MGP_DBA2J_G0008576	miRNA gene	Chr3:86714673-86714752 (+)
FVB/NJ	MGP_FVBNJ_G0008599	miRNA gene	Chr3:85048892-85048971 (+)
LP/J	MGP_LPJ_G0008669	miRNA gene	Chr3:91408203-91408282 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008562	miRNA gene	Chr3:103150123-103150202 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008834	miRNA gene	Chr3:89228213-89228292 (+)
PWK/PhJ	MGP_PWKPhJ_G0008356	miRNA gene	Chr3:86603633-86603712 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0008211	miRNA gene	Chr3:88399389-88399468 (+)
WSB/EiJ	MGP_WSBEiJ_G0008516	miRNA gene	Chr3:89620805-89620884 (+)

Human Ortholog

MIR190B, microRNA 190b

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR190B, microRNA 190b
Synonyms

mir-190b, MIRN190B
Links

HGNC:33656

NCBI Gene ID: 100126346
Chr Location

chr1:154193665-154193743 (-) GRCh38

MGI Vertebrate Homology

Mir190b stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR190B
Gene Tree

Mir190b

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References

1 with disease annotations

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Mir190b
Find Mice (IMSR)

1 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000077996 (Evidence)
NCBI Gene

100124481

Representative Sequences				Length	Strain/Species	Flank
	genomic	100124481	NCBI Gene Model \| MGI Sequence Detail	80	C57BL/6J	± kb
	transcript	NR_030543	RefSeq \| MGI Sequence Detail	80	C57BL/6

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All nucleic 1

Other 1

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miRBase

MI0005478

Summaries

All 14

Diseases 1

Gene Ontology 1

Phenotypes 5
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:297550 Hong H, et al., In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor. PLoS Genet. 2020 Nov;16(11):e1009168

TSS for Mir190b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30152	Chr3:89975467-89975474 (+)	-1,856 bp
Tssr30153	Chr3:89976374-89976380 (+)	-950 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24