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Tmem35b Gene Detail
Summary
  • Symbol
    Tmem35b
  • Name
    transmembrane protein 35B
  • Synonyms
    Zmym6nb
  • Feature Type
    protein coding gene
  • IDs
    MGI:3758095
    NCBI Gene: 100039968
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:127019836-127023453 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 61.29 cM
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3758095
 protein coding gene Chr4:127017484-127023453 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028793
 protein coding gene Chr4:128857931-128863850 (+)
A/J MGP_AJ_G0028752
 protein coding gene Chr4:123777457-123783376 (+)
AKR/J MGP_AKRJ_G0028705
 protein coding gene Chr4:127176427-127182380 (+)
BALB/cJ MGP_BALBcJ_G0028775
 protein coding gene Chr4:124345411-124351330 (+)
C3H/HeJ MGP_C3HHeJ_G0028489
 protein coding gene Chr4:127255612-127261531 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029217
 protein coding gene Chr4:133764940-133770893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026490
 protein coding gene Chr4:116899536-116905552 (+)
CAST/EiJ MGP_CASTEiJ_G0027922
 protein coding gene Chr4:125369271-125375226 (+)
CBA/J MGP_CBAJ_G0028455
 protein coding gene Chr4:137016041-137021960 (+)
DBA/2J MGP_DBA2J_G0028604
 protein coding gene Chr4:124220116-124226035 (+)
FVB/NJ MGP_FVBNJ_G0028571
 protein coding gene Chr4:122884799-122890718 (+)
LP/J MGP_LPJ_G0028705
 protein coding gene Chr4:129146659-129152578 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028597
 protein coding gene Chr4:142016896-142022815 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029255
 protein coding gene Chr4:127550700-127556619 (+)
PWK/PhJ MGP_PWKPhJ_G0027643
 protein coding gene Chr4:120717989-120723916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027469
 protein coding gene Chr4:123365365-123371396 (+)
WSB/EiJ MGP_WSBEiJ_G0028002
 protein coding gene Chr4:127660625-127666578 (+)



Homology
more
  • Human Ortholog
    TMEM35B, transmembrane protein 35B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM35B, transmembrane protein 35B
  • Synonyms
    ZMYM6NB
  • Links
    NCBI Gene ID: 100506144
    neXtProt AC: NX_Q8NCS4
    UniProt: Q8NCS4

  • Chr Location
    chr1:34981380-34985347 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Tmem35b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    20 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100039968 NCBI Gene Model | MGI Sequence Detail 3618 C57BL/6J ±  kb
transcript NM_001099319 RefSeq | MGI Sequence Detail 1139 C57BL/6  
polypeptide Q3U0Y2 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory