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Cfap73 Gene Detail
Summary
  • Symbol
    Cfap73
  • Name
    cilia and flagella associated protein 73
  • Synonyms
    Ccdc42b, Gm5988
  • Feature Type
    protein coding gene
  • IDs
    MGI:3779542
    NCBI Gene: 546886
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:120766400-120772300 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3779542
 protein coding gene Chr5:120766400-120772300 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030010
 protein coding gene Chr5:124013280-124019179 (-)
A/J MGP_AJ_G0029974
 protein coding gene Chr5:118874000-118879899 (-)
AKR/J MGP_AKRJ_G0029913
 protein coding gene Chr5:122711724-122717623 (-)
BALB/cJ MGP_BALBcJ_G0029985
 protein coding gene Chr5:120291484-120297383 (-)
C3H/HeJ MGP_C3HHeJ_G0029705
 protein coding gene Chr5:123245397-123251296 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030440
 protein coding gene Chr5:128668167-128674067 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027666
 protein coding gene Chr5:113584501-113590366 (-)
CAST/EiJ MGP_CASTEiJ_G0029114
 protein coding gene Chr5:122374653-122380571 (-)
CBA/J MGP_CBAJ_G0029673
 protein coding gene Chr5:133661455-133667354 (-)
DBA/2J MGP_DBA2J_G0029823
 protein coding gene Chr5:118960053-118965953 (-)
FVB/NJ MGP_FVBNJ_G0029779
 protein coding gene Chr5:117886917-117892818 (-)
LP/J MGP_LPJ_G0029911
 protein coding gene Chr5:124470412-124476311 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029810
 protein coding gene Chr5:137627446-137633345 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030481
 protein coding gene Chr5:122290787-122296686 (-)
PWK/PhJ MGP_PWKPhJ_G0028827
 protein coding gene Chr5:117721426-117727331 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028666
 protein coding gene Chr5:119954188-119960064 (-)
WSB/EiJ MGP_WSBEiJ_G0029189
 protein coding gene Chr5:122882993-122888930 (-)



Homology
more
  • Human Ortholog
    CFAP73, cilia and flagella associated protein 73
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP73, cilia and flagella associated protein 73
  • Synonyms
    CCDC42B, MIA2
  • Links
    NCBI Gene ID: 387885
    neXtProt AC: NX_A6NFT4
    UniProt: A6NFT4

  • Chr Location
    12q24.13; chr12:113149724-113159276 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Cfap73
  • Find Mice (IMSR)
    17 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 546886 NCBI Gene Model | MGI Sequence Detail 5901 C57BL/6J ±  kb
transcript NM_001195094 RefSeq | MGI Sequence Detail 921 ZRU/MplStud  
polypeptide J3QPZ5 UniProt | EBI | MGI Sequence Detail 306 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032191 cilia- and flagella-associated protein 73
    (term hierarchy)
  • InterPro Domains
    IPR051147 Cilia- and flagella-associated domain-containing protein
    IPR025252 Domain of unknown function DUF4200
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory