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Sirpb1b Gene Detail
Summary
  • Symbol
    Sirpb1b
  • Name
    signal-regulatory protein beta 1B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3779828
    NCBI Gene: 668101
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:15560814-15640127 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 3.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2352 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3779828
 protein coding gene Chr3:15560811-15640127 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027081
 protein coding gene Chr3:12527196-13050306 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0027056
 protein coding gene Chr3:12675684-12732110 (-)
C3H/HeJ MGP_C3HHeJ_G0026795
 protein coding gene Chr3:13023997-13061137 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027500
 protein coding gene Chr3:13476728-13570888 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024862
 protein coding gene Chr3:11056015-11090238 (-)
CAST/EiJ MGP_CASTEiJ_G0026252
 protein coding gene Chr3:12834681-12845133 (-)
CBA/J MGP_CBAJ_G0026773
 protein coding gene Chr3:13751523-13850785 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0026875
 protein coding gene Chr3:11856700-12311343 (-)
LP/J MGP_LPJ_G0027019
 protein coding gene Chr3:13309898-13355176 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025792
 protein coding gene Chr3:12383768-12606780 (-)
WSB/EiJ MGP_WSBEiJ_G0026323
 protein coding gene Chr3:12521120-12560138 (-)



Homology
more
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Synonyms
    CD172b, SIRP-BETA-1
  • Links
    NCBI Gene ID: 10326
    neXtProt AC: NX_O00241, NX_Q5TFQ8
    UniProt: O00241, Q5TFQ8

  • Chr Location
    20p13; chr20:1561385-1620061 (-)  GRCh38
  • Human Ortholog
    SIRPG, signal regulatory protein gamma
  • Synonyms
    bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma
  • Links
    NCBI Gene ID: 55423
    neXtProt AC: NX_Q9P1W8
    UniProt: Q9P1W8

  • Chr Location
    20p13; chr20:1629152-1686455 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 668101 NCBI Gene Model | MGI Sequence Detail 79314 C57BL/6J ±  kb
transcript NM_001173460 RefSeq | MGI Sequence Detail 1496 C57BL/6  
polypeptide NP_001166931 RefSeq | MGI Sequence Detail 391 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR051755 Immunoglobulin-like Cell Surface Receptor
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR013106 Immunoglobulin V-set domain
  • GlyGen
    A0A0A6YXN8 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Diseases 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory