Ndufb1 MGI Mouse Gene Detail - MGI:3780865 - NADH:ubiquinone oxidoreductase subunit B1

Ndufb1 Gene Detail

Symbol

Ndufb1
Name

NADH:ubiquinone oxidoreductase subunit B1
Synonyms

Gm2695, Ndufb1-ps

Feature Type

protein coding gene
IDs

MGI:3780865
NCBI Gene: 102631912
Alliance

gene page
Transcription Start Sites

13 TSS

Sequence Map

Chr12:101934355-101941997 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 51.33 cM
Mapping Data

1 experiment

SNPs within 2kb

294 from dbSNP Build 142
Strain Annotations

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3780865	protein coding gene	Chr12:101934349-101943327 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

NDUFB1, NADH:ubiquinone oxidoreductase subunit B1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

NDUFB1, NADH:ubiquinone oxidoreductase subunit B1
Synonyms

CI-MNLL, CI-SGDH, MNLL
Links

HGNC:7695

NCBI Gene ID: 4707

neXtProt AC: NX_O75438

UniProt: O75438
Chr Location

14q32.12; chr14:92116122-92121917 (-) GRCh38

MGI Vertebrate Homology

Ndufb1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: NDUFB1
Gene Tree

Ndufb1

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

123
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

121
Genomic Mutations

1 involving Ndufb1
Find Mice (IMSR)

1 strains or lines available

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All GO Annotations

14
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

3

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ndufb1

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All Sequences

19
RefSeq

4
UniProt

1

Ensembl

ENSMUSG00000113902 (Evidence)
NCBI Gene

102631912

			Length	Strain/Species	Flank
genomic	102631912	NCBI Gene Model \| MGI Sequence Detail	7643	C57BL/6J	± kb
transcript	NM_001378525	RefSeq \| MGI Sequence Detail	339	C57BL/6
polypeptide	P0DN34	UniProt \| EBI \| MGI Sequence Detail	57	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000011083 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

(term hierarchy)
PDB

6G2J, 6G72, 6ZR2, 6ZTQ, 7AK5, 7AK6, 7B93, 7PSA, 8C2S, 8CA3, 8CA5, 8OLT, 8OM1, 8PW5, 8PW6, 8PW7, 8RGP, 8RGQ, 8RGR, 8RGT
InterPro Domains

IPR012575 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, NDUB1
GlyGen

P0DN34 1 site, 1 O-linked glycan (1 site)

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All nucleic 3

cDNA 3

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MGI:5883138, MGI:6391117

Summaries

All 21

Gene Ontology 7

Phenotypes 7
Earliest

J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
Latest

J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071

TSS for Ndufb1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr117393	Chr12:101943156-101943173 (-)	-1,168 bp
Tssr117392	Chr12:101943136-101943146 (-)	-1,144 bp
Tssr117391	Chr12:101942541-101942560 (-)	-554 bp
Tssr117390	Chr12:101942524-101942538 (-)	-534 bp
Tssr117389	Chr12:101942463-101942507 (-)	-488 bp
Tssr117388	Chr12:101942282-101942294 (-)	-291 bp
Tssr117387	Chr12:101942238-101942243 (-)	-244 bp
Tssr117386	Chr12:101942194-101942205 (-)	-203 bp
Tssr117385	Chr12:101942172-101942183 (-)	-181 bp
Tssr3923	Chr12:101942142-101942145 (-)	-147 bp
Tssr117384	Chr12:101942024-101942035 (-)	-33 bp
Tssr117383	Chr12:101941942-101942005 (-)	23 bp
Tssr117382	Chr12:101938109-101938122 (-)	3,881 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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