About   Help   FAQ
Dynlt1f Gene Detail
Summary
  • Symbol
    Dynlt1f
  • Name
    dynein light chain Tctex-type 1F
  • Synonyms
    Dynlt1e
  • Feature Type
    protein coding gene
  • IDs
    MGI:3780996
    NCBI Gene: 100040531
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr17:6914001-6923299 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 4.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3780996
protein coding gene Chr17:6914001-6923338 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023113
protein coding gene Chr17:3620450-3626852 (+)
A/J MGP_AJ_G0023082
protein coding gene Chr17:3525998-3542367 (+)
AKR/J MGP_AKRJ_G0023049
protein coding gene Chr17:3926117-3928131 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0022847
protein coding gene Chr17:3824029-3830317 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0022949
protein coding gene Chr17:3606497-3608511 (-)
FVB/NJ MGP_FVBNJ_G0022921
protein coding gene Chr17:3291145-3301878 (-)
LP/J MGP_LPJ_G0023015
protein coding gene Chr17:3567488-3923409 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022942
protein coding gene Chr17:3788452-3794546 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023551
protein coding gene Chr17:3878341-3880351 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0022414
protein coding gene Chr17:3809563-3816658 (-)



Homology
more
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Synonyms
    CW-1, TCTEL1, tctex-1, TCTEX1
  • Links
    NCBI Gene ID: 6993
    neXtProt AC: NX_P63172
    UniProt: P63172

  • Chr Location
    6q25.3; chr6:158636474-158644743 (-)  GRCh38

Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    350 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000095677 Ensembl Gene Model | MGI Sequence Detail 9299 C57BL/6J ±  kb
transcript ENSMUST00000179554 Ensembl | MGI Sequence Detail 771 Not Applicable  
polypeptide ENSMUSP00000135978 Ensembl | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
Other
Accession IDs
less
MGI:3781053
References
more
  • Summaries
    All 363
    Diseases 6
    Gene Ontology 2
    Phenotypes 350
  • Earliest
    J:11036 Howard CA, et al., Genetic and molecular analysis of the proximal region of the mouse t-complex using new molecular probes and partial t-haplotypes. Genetics. 1990 Dec;126(4):1103-14
  • Latest
    J:354984 Emili M, et al., Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model. Neuropharmacology. 2024 Sep 27;261:110170

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory