Pramel42 MGI Mouse Gene Detail - MGI:3781318

Pramel42 Gene Detail

Symbol

Pramel42
Name

PRAME like 42
Synonyms

Gm3139

Feature Type

protein coding gene
IDs

MGI:3781318
NCBI Gene: 100041102
Alliance

gene page

Sequence Map

Chr5:94674143-94686226 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 47.29 cM
Mapping Data

1 experiment

SNPs within 2kb

1 from dbSNP Build 142
Strain Annotations

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3781318	protein coding gene	Chr5:94674143-94694282 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

PRAMEF1, PRAME family member 1

Vertebrate Orthologs

22

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PRAMEF1, PRAME family member 1
Links

HGNC:28840

NCBI Gene ID: 65121

neXtProt AC: NX_O95521

UniProt: O95521
Chr Location

1p36.21; chr1:12791397-12796628 (+) GRCh38

Human Ortholog

PRAMEF10, PRAME family member 10
Links

HGNC:27997

NCBI Gene ID: 343071

neXtProt AC: NX_O60809

UniProt: O60809
Chr Location

1p36.21; chr1:12892896-12898270 (-) GRCh38

Human Ortholog

PRAMEF11, PRAME family member 11
Links

HGNC:14086

NCBI Gene ID: 440560

neXtProt AC: NX_O60813

UniProt: O60813
Chr Location

1p36.21; chr1:12824605-12831410 (-) GRCh38

Human Ortholog

PRAMEF12, PRAME family member 12
Links

HGNC:22125

NCBI Gene ID: 390999

neXtProt AC: NX_O95522

UniProt: O95522
Chr Location

1p36.21; chr1:12773738-12777906 (+) GRCh38

Human Ortholog

PRAMEF13, PRAME family member 13
Links

HGNC:13262

NCBI Gene ID: 400736

neXtProt AC: NX_Q5VWM6

UniProt: Q5VWM6
Chr Location

1p36.21; chr1:13196188-13201409 (-) GRCh38

Human Ortholog

PRAMEF15, PRAME family member 15
Links

HGNC:26764

NCBI Gene ID: 653619

neXtProt AC: NX_P0DUQ1, NX_P0DUQ2

UniProt: P0DUQ1
Chr Location

1p36.21; chr1:13315581-13322598 (+) GRCh38

Human Ortholog

PRAMEF17, PRAME family member 17
Links

HGNC:29485

NCBI Gene ID: 391004

neXtProt AC: NX_Q5VTA0

UniProt: Q5VTA0
Chr Location

1p36.21

Human Ortholog

PRAMEF18, PRAME family member 18
Links

HGNC:30693

NCBI Gene ID: 391003

neXtProt AC: NX_Q5VWM3

UniProt: Q5VWM3
Chr Location

1p36.21; chr1:13222695-13226154 (-) GRCh38

Human Ortholog

PRAMEF19, PRAME family member 19
Links

HGNC:24908

NCBI Gene ID: 645414

neXtProt AC: NX_Q5SWL8

UniProt: Q5SWL8
Chr Location

1p36.21; chr1:13368431-13371947 (-) GRCh38

Human Ortholog

PRAMEF2, PRAME family member 2
Synonyms

DJ845O24.3
Links

HGNC:28841

NCBI Gene ID: 65122

neXtProt AC: NX_O60811

UniProt: O60811
Chr Location

1p36.21; chr1:12857086-12861909 (+) GRCh38

Human Ortholog

PRAMEF20, PRAME family member 20
Synonyms

PRAMEF21
Links

HGNC:25224

NCBI Gene ID: 645425

neXtProt AC: NX_Q5VT98

UniProt: Q5VT98
Chr Location

1p36.21; chr1:13410450-13421328 (+) GRCh38

Human Ortholog

PRAMEF25, PRAME family member 25
Links

HGNC:49179

NCBI Gene ID: 441873

neXtProt AC: NX_A6NGN4

UniProt: A6NGN4
Chr Location

1p36.21; chr1:13068677-13077884 (+) GRCh38

Human Ortholog

PRAMEF26, PRAME family member 26
Synonyms

PRAMEF25
Links

HGNC:49178

NCBI Gene ID: 645359

neXtProt AC: NX_A6NGN4

UniProt: H0Y7S4
Chr Location

1p36.21

Human Ortholog

PRAMEF27, PRAME family member 27
Links

HGNC:51234

NCBI Gene ID: 101929983

neXtProt AC: NX_A3QJZ7

UniProt: A3QJZ7
Chr Location

chr1:13049476-13056575 (-) GRCh38

Human Ortholog

PRAMEF33, PRAME family member 33
Synonyms

PRAMEF33P
Links

HGNC:49193

NCBI Gene ID: 645382

neXtProt AC: NX_A0A0G2JMD5

UniProt: A0A0G2JMD5
Chr Location

1p36.21; chr1:13303539-13308907 (+) GRCh38

Human Ortholog

PRAMEF4, PRAME family member 4
Links

HGNC:31971

NCBI Gene ID: 400735

neXtProt AC: NX_O60810

UniProt: O60810
Chr Location

1p36.21; chr1:12879212-12886201 (-) GRCh38

Human Ortholog

PRAMEF5, PRAME family member 5
Synonyms

PRAMEF23, PRAMEF5L
Links

HGNC:27995

NCBI Gene ID: 343068

neXtProt AC: NX_Q5TYX0

UniProt: Q5TYX0
Chr Location

1p36.21; chr1:13254198-13263435 (+) GRCh38

Human Ortholog

PRAMEF6, PRAME family member 6
Links

HGNC:30583

NCBI Gene ID: 440561

neXtProt AC: NX_Q5VXH4

UniProt: Q5VXH4
Chr Location

1p36.21; chr1:12938472-12947580 (-) GRCh38

Human Ortholog

PRAMEF7, PRAME family member 7
Links

HGNC:28415

NCBI Gene ID: 441871

neXtProt AC: NX_Q5VXH5

UniProt: Q5VXH5
Chr Location

1p36.21; chr1:12916610-12920751 (+) GRCh38

Human Ortholog

PRAMEF8, PRAME family member 8
Synonyms

PRAMEF24
Links

HGNC:24074

NCBI Gene ID: 391002

neXtProt AC: NX_Q5VWM4

UniProt: Q5VWM4
Chr Location

1p36.21; chr1:13281304-13285137 (-) GRCh38

Human Ortholog

PRAMEF9, PRAME family member 9
Links

HGNC:27996

NCBI Gene ID: 343070

UniProt: P0DUQ2
Chr Location

1p36.21; chr1:13171848-13179459 (+) GRCh38

MGI Vertebrate Homology

Pramel42 stringent orthology
21 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: PRAMEF1, PRAMEF10, PRAMEF11, PRAMEF12, PRAMEF13, PRAMEF15, PRAMEF17, PRAMEF18, PRAMEF19, PRAMEF2, PRAMEF20, PRAMEF25, PRAMEF26, PRAMEF27, PRAMEF33, PRAMEF4, PRAMEF5, PRAMEF6, PRAMEF7, PRAMEF8, PRAMEF9
Protein SuperFamily

PRAME
Gene Tree

Pramel42

Diseases

1 with human PRAME associations

				Human Disease	Mouse Models
				myeloid leukemia IDs myeloid leukemia DOID:8692 DOID:8878 DOID:8879 DOID:8910 DOID:9066 DOID:9126 ICD10CM:C92 ICD9CM:205 ICD9CM:205.9 MESH:D007951 NCI:C3172 UMLS_CUI:C0023470

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Radiation induced

1
Spontaneous

1
Genomic Mutations

3 involving Pramel42
Find Mice (IMSR)

7 strains or lines available

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All GO Annotations

8
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

4

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

18
RefSeq

4
UniProt

2
CCDS

CCDS57361.1

Ensembl

ENSMUSG00000095074 (Evidence)
NCBI Gene

100041102

			Length	Strain/Species	Flank
genomic	100041102	NCBI Gene Model \| MGI Sequence Detail	12084	C57BL/6J	± kb
transcript	NM_001243937	RefSeq \| MGI Sequence Detail	2079	C57BL/6
polypeptide	NP_001230867	RefSeq \| MGI Sequence Detail	481	C57BL/6

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UniProt

2 Sequences
InterPro Domains

IPR032675 Leucine-rich repeat domain superfamily

IPR026271 PRAME

IPR050694 PRAME domain-containing protein

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All nucleic 4

cDNA 4

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MGI:6430540

Summaries

All 17

Gene Ontology 2

Phenotypes 6
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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